Broad Institute
JANUARY 14, 2025
Gene editing extends lifespan in mouse model of prion disease By Allessandra DiCorato January 14, 2025 Breadcrumb Home Gene editing extends lifespan in mouse model of prion disease A single-letter edit in DNA reduces levels of the disease-causing prion protein in the brain and could lead to a preventative, one-time treatment for the deadly neurodegenerative disorder.
BioPharma Drive: Drug Pricing
JANUARY 16, 2025
Pharma dealmaking for drugs invented in China is putting pressure on U.S. biotechs to compete harder, according to investors and executives interviewed by BioPharma Dive at the J.P. Morgan Healthcare Conference.
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Nvidia Developer: Drug Discovery
JANUARY 13, 2025
Traditional computational drug discovery relies almost exclusively on highly task-specific computational models for hit identification and lead optimization. Traditional computational drug discovery relies almost exclusively on highly task-specific computational models for hit identification and lead optimization. Adapting these specialized models to new tasks requires substantial time, computational power, and expertisechallenges that grow when researchers simultaneously work across multiple ta
Science Daily: Pharmacology News
JANUARY 13, 2025
Researchers have developed a drastically smaller and more energy efficient method of creating coveted photon pairs that influence each other from any distance. The technology could transform computing, telecommunications, and sensing.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Drugs.com
JANUARY 13, 2025
MONDAY, Jan. 13, 2025 (HealthDay news) -- The sleep aid Ambien could be allowing toxic proteins to pollute the brain, potentially increasing a persons risk of disorders like Alzheimers disease.Drugs like the main ingredient in Ambien, zolpidem, sup.
Drug Target Review
JANUARY 14, 2025
Drug discovery scientists spend their days developing and testing complex hypotheses, leveraging data and expertise through workflows that utilise available tools. Operating a workflow, such as the one described in Figure 1, involves several key considerations that affect both the accuracy of results and the efficiency of the research process. Defining the research question A well-defined research question is the cornerstone of an effective scientific workflow in drug discovery.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Science Daily: Pharmacology News
JANUARY 15, 2025
New proteins not found in nature have now been designed to counteract certain highly poisonous components of snake venom. The deep learning, computational methods for developing these toxin-neutralizing proteins offer hope for creating safer, more cost-effective and more readily available therapeutics than those currently in use. Each year more than 2 million people suffer snakebites.
BioPharma Drive: Drug Pricing
JANUARY 13, 2025
The company lost more than $3 billion in market value after cutting its forecast for 2025 revenue from its COVID-19 and RSV vaccines.
Drugs.com
JANUARY 16, 2025
THURSDAY, Jan. 16, 2025 -- Cutting-edge targeted therapies are pushing back the line between life and death for cancer patients.However, these targeted cancer drugs frequently arent benefitting members of ethnic and racial minorities in the U.S., a.
Drug Patent Watch
JANUARY 15, 2025
Identifying drug patents is crucial for various stakeholders, including researchers, legal professionals, and business strategists. While Google Patents is a widely used tool for searching patent information, it may not be the most effective solution for identifying drug patents. This article explores the limitations of Google Patents in this context and suggests alternative approaches.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Perficient: Drug Development
JANUARY 14, 2025
In this blog post, I will share my journey of developing a Python-based solution to remove strikethrough text from PDFs. This solution is specifically designed for PDFs where strikethrough is applied as a style rather than an annotation. The Challenge Strikethrough text in PDFs can be tricky to handle, mainly when applied as a style. Standard PDF manipulation libraries often fall short in these cases.
Science Daily: Pharmacology News
JANUARY 10, 2025
A whitish, grey patch that sometimes appears in the night sky alongside the northern lights has now been explained.
BioPharma Drive: Drug Pricing
JANUARY 14, 2025
The company said it overestimated demand of its obesity and diabetes drugs in the fourth quarter, but projected a further ramp-up in sales this year.
Drugs.com
JANUARY 17, 2025
FRIDAY, Jan. 17, 2025 -- Women past menopause can protect themselves from future fractures through infrequent, cheap IV infusions of a bone-strengthening drug. Women 50 to 60 who got two IV infusions of zoledronate (Reclast) within five years had a.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
PPD
JANUARY 15, 2025
As clinical trials become increasingly complex, particularly in decentralized trials and rare disease studies, sponsors experience increased challenges in site selection, forecasting and resourcing, and patient recruitment and enrollment. Advanced artificial intelligence (AI) and machine learning solutions are revolutionizing critical challenge areas.
Drug Patent Watch
JANUARY 14, 2025
UZEDY (risperidone) Teva Patent: 10,736,965 Expiration: Jan 12, 2025 See More … For more information on how DrugPatentWatch can help with your pharmaceutical business intelligence needs, contact admin@DrugPatentWatch.com or visit www.DrugPatentWatch.
Science Daily: Pharmacology News
JANUARY 10, 2025
A new study has found that the composition of your gut microbiome helps predict how likely you are to succumb to potentially life-threatening infection with Klebsiella pneumoniae, E.coli and other bugs -- and it may be altered by changing your diet.
BioPharma Drive: Drug Pricing
JANUARY 10, 2025
The director of the FDA's main drug review office will exit on Jan. 18, according to an email sent to staff. Her departure is one of several announced by high-ranking FDA leaders ahead of the coming administration change.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
JANUARY 14, 2025
TUESDAY, Jan. 14, 2025 -- A popular diabetes drug can provide protection against skin cancers, a new study says. Metformin significantly reduces people’s risk of developing basal cell cancers or squamous cell cancers, the two most common skin.
DS in Pharmatics
JANUARY 11, 2025
Regulatory compliance defines success in biopharmaceuticals and medical devices. A missed step can lead to recalls, financial losses, or patient harm. Quality assurance (QA) consultants, like DSI, help companies tackle these risks. Our expertise strengthens compliance strategies, mitigates issues, and boosts operational efficiency.
Perficient: Drug Development
JANUARY 14, 2025
Imagine youre a skilled craftsman working in a massive warehouse. Every day, your task is to process thousands of unique items and ensure that each one is properly logged and stored. But lets face it mistakes happen. Sometimes an item gets mislabeled or damaged, and you need to know which ones to fix, and which ones made it safely through. In Salesforce, when working with a batch class that processes thousands or even millions of records, Database.SaveResult acts as your trusty supervisor, keep
Science Daily: Pharmacology News
JANUARY 13, 2025
A new study shows that the risk of developing dementia anytime after age 55 among Americans is 42%, more than double the risk reported by older studies.
BioPharma Drive: Drug Pricing
JANUARY 14, 2025
Young drugmakers confront several harsh realities this year, among them a contracting sector and competition from China.
Drugs.com
JANUARY 15, 2025
WEDNESDAY, Jan. 15, 2025 -- The U.S Food and Drug Administration has amended its color additive regulations to no longer allow the use of Federal Food, Drug, and Cosmetic Act (FD&C Act) Red No. 3 in food and ingested drugs.FD&C Red No. 3 is.
Drug Patent Watch
JANUARY 14, 2025
In the fast-paced world of pharmaceuticals, negotiations play a pivotal role in shaping the industry’s landscape. From mergers and acquisitions to licensing agreements and pricing discussions, these complex interactions demand a unique blend of scientific knowledge, business acumen, and interpersonal skills. Let’s dive into the intricacies of pharmaceutical negotiations, exploring valuable lessons, current trends, and strategies for success.
FDA Law Blog: Drug Discovery
JANUARY 12, 2025
By Charles G. Raver & James E. Valentine & Ellis Unger & Frank J. Sasinowski On December 5, 2024, FDA published a new draft guidance on accelerated approval providing a much needed and substantial update to its guidance on the pathway. FDAs application and use of accelerated approval has evolved dramatically since it was first developed by the Agency to help address the HIV/AIDS epidemic in the late 1980s.
Science Daily: Pharmacology News
JANUARY 15, 2025
Researchers have identified nine mutations in a bird flu strain from a person in Texas. Bad news: this strain is more capable of causing disease and replicates better in the brain. Good news: approved antivirals are still effective.
BioPharma Drive: Drug Pricing
JANUARY 13, 2025
Intra-Cellular has had success selling Caplyta, a brain-rebalancing drug that's approved to treat schizophrenia and bipolar depression.
Drugs.com
JANUARY 14, 2025
TUESDAY, Jan. 14, 2025 -- A deadly bird flu outbreak has wreaked havoc on U.S. chicken farms, claiming the lives of over 20 million egg-laying chickens last quarter, marking the worst impact on America's egg supply since the outbreak began in.
Drug Patent Watch
JANUARY 13, 2025
Biosimilars have emerged as a game-changing force, promising to revolutionize patient access to life-saving biologics while simultaneously reducing healthcare costs. As we delve into the intricate world of biosimilar market dynamics, we’ll explore how these complex molecules are reshaping treatment paradigms across diverse patient populations.
Perficient: Drug Development
JANUARY 14, 2025
Kristen Quick, Director at Perficient, shared her insights on the transformative potential of Salesforce Life Sciences Cloud for pharmaceutical and med tech organizations, highlighting its ability to drive innovation and improve outcomes. As the healthcare landscape continues to evolve, innovative solutions like Life Sciences Cloud are becoming essential for driving efficiency, improving patient care, and accelerating time to market: Introduction to Kristen Quick Kristen Quick is a director i
Science Daily: Pharmacology News
JANUARY 13, 2025
Radiation-induced mutation is unlikely to have induced genetic differences between dog populations in Chornobyl City and the nearby Chornobyl Nuclear Power Plant.
BioPharma Drive: Drug Pricing
JANUARY 12, 2025
The biotech plans to use the funding to advance clinical testing of an epigenetic silencing therapy it hopes could treat chronic hepatitis B infections.
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