Drugs.com
NOVEMBER 19, 2024
TUESDAY, Nov. 19, 2024 -- Women who won't leave the house without makeup or a spritz of hairspray may want to think twice about those habits when they're pregnant or breastfeeding.New research links these and other personal care products, including.
Perficient: Drug Development
NOVEMBER 19, 2024
This post is the third in a series of four about estimating project hours. Part 1: Sandbagging & Lowballing Part 2: Dependencies & Creep Part 3: Assumptions & Uncertainty Part 4: The Emotional Conclusion The emotional finale is here! Don’t worry, this isn’t about curling up in a ball and crying – we’ve already done that. This final installment of my series on project estimating is all about navigating the emotions of everyone involved and trying to avoid frustration.
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Science Daily: Pharmacology News
NOVEMBER 16, 2024
The Earth's total amount of freshwater dropped abruptly starting in May 2014 and has remained low ever since. The shift could indicate Earth's continents have entered a persistently drier phase.
Drugs.com
NOVEMBER 18, 2024
MONDAY, Nov. 18, 2024 -- Drugs already taken by millions of diabetes patients appear to also help slash asthma attacks by up to 70%, new British research shows.The two drugs are metformin, one of the most widely used diabetes medications, and the.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Nvidia Developer: Drug Discovery
NOVEMBER 13, 2024
The ability to compare the sequences of multiple related proteins is a foundational task for many life science researchers. This is often done in the form of a. The ability to compare the sequences of multiple related proteins is a foundational task for many life science researchers. This is often done in the form of a multiple sequence alignment (MSA), and the evolutionary information retrieved from these alignments can yield insights into protein structure, function, and evolutionary history.
BioPharma Drive: Drug Pricing
NOVEMBER 15, 2024
At an event hosted by BioPharma Dive, drugmaker executives and investors discussed the importance of focus, smart spending and maintaining lines of sight to the clinic.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Science Daily: Pharmacology News
NOVEMBER 13, 2024
How much land, water, and other resources does our lifestyle require? And how can we adapt this lifestyle to stay within the limits of what the Earth can give? A new article tackles these questions.
BioPharma Drive: Drug Pricing
NOVEMBER 14, 2024
The company is paying China-based biotech LaNova Medicines $588 million for the type of dual-pronged antibody drug that recently bested Keytruda in a clinical trial.
Nvidia Developer: Drug Discovery
NOVEMBER 18, 2024
AI models for science are often trained to make predictions about the workings of nature, such as predicting the structure of a biomolecule or the properties of. AI models for science are often trained to make predictions about the workings of nature, such as predicting the structure of a biomolecule or the properties of a new solid that can become the next battery material.
PLOS: DNA Science
NOVEMBER 14, 2024
In 2019, I wrote about how sequencing the genomes of newborns might compromise their privacy if genetic information was not adequately protected as they grew up. Now five years later, researchers are recognizing a perhaps unexpected benefit of newborn DNA analysis – explaining seemingly unrelated symptoms in relatives. Newborn Screening for Metabolites, not DNA Screening newborns for telltale molecules other than DNA has been around for decades.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drugs.com
NOVEMBER 19, 2024
TUESDAY, Nov. 19, 2024 -- New research suggests that a procedure now regarded as Plan B when patients have episodes of rapid heartbeat after a heart attack should be the go-to treatment.Ablation is a minimally invasive procedure to treat abnormal.
Science Daily: Pharmacology News
NOVEMBER 19, 2024
Up until recently, habituation -- a simple form of learning -- was deemed the exclusive domain of complex organisms with brains and nervous systems, such as worms, insects, birds, and mammals. But a new study offers compelling evidence that even tiny single-cell creatures such as ciliates and amoebae, as well as the cells in our own bodies, could exhibit habituation akin to that seen in more complex organisms with brains.
BioPharma Drive: Drug Pricing
NOVEMBER 14, 2024
A key regulatory committee sided against the drug this summer. But an appeal from Eisai appears to have worked, teeing Leqembi up for authorization in a major market.
Practical Cheminformatics
NOVEMBER 16, 2024
Introduction Dataset splitting is one topic that doesn’t get enough attention when discussing machine learning (ML) in drug discovery. The data is typically divided into training and test sets when developing and evaluating an ML model. The model is trained on the training set, and its performance is assessed on the test set. If hyperparameter tuning is required, a validation set is also included.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drug Channels
NOVEMBER 13, 2024
Uh oh. As I predicted, the stand-alone Medicare Part D prescription drug plans (PDP) market is vanishing. For 2025, DCI’s exclusive analysis of Center for Medicare & Medicaid Services’ (CMS) data reveals that the number of PDPs will drop to a historic low. What’s more, the share of plans with a preferred cost sharing pharmacy network will fall to its lowest rate in more than 10 years.
Drugs.com
NOVEMBER 15, 2024
FRIDAY, Nov. 15, 2024 -- Waning vaccine coverage has fueled a 20% spike in measles cases worldwide, with 10.3 million people struck by the preventable illness in 2023, health officials reported Wednesday."Inadequate immunization coverage globally.
Science Daily: Pharmacology News
NOVEMBER 15, 2024
More time spent sitting, reclining or lying down during the day may increase the risk of cardiovascular disease (CVD) and death, according to a new study. More than roughly 10-and-a-half hours of sedentary behavior per day was significantly linked with future heart failure (HF) and cardiovascular (CV) death, even among people meeting recommended levels of exercise.
BioPharma Drive: Drug Pricing
NOVEMBER 13, 2024
Biotheus’ antibody drug targets PD-L1 and VEGF, a design that’s high on drugmakers’ radars after the success of Summit Therapeutics’ ivonescimab over Keytruda.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drug Patent Watch
NOVEMBER 14, 2024
The pharmaceutical industry has undergone significant transformations in recent years, with the increasing complexity of clinical trials and the need for cost and time efficiency driving the growth of contract research organizations (CROs).
Drug Channels
NOVEMBER 19, 2024
In Medicare Part D in 2025: Preferred Pharmacy Networks Fade in a Collapsing PDP Market , I documented the Inflation Reduction Act’s (IRA) disruption to Medicare Part D prescription drug plans (PDPs). Today, we examine the seven largest retail chains’ participation in the 12 major 2025 Part D networks that the five largest plan sponsors will offer. As always, we provide you with a handy table for tallying each chain’s participation and changes from 2024 to 2025.
Drugs.com
NOVEMBER 19, 2024
TUESDAY, Nov. 19, 2024 -- As climate changes sends summer temperatures higher worldwide, new research finds most urban residents don't have a key source of cooling shade: trees.A study of eight cities around the globe found that only two -- Seattle.
Science Daily: Pharmacology News
NOVEMBER 13, 2024
An asteroid struck Mars 11 million years ago and sent pieces of the red planet hurtling through space. One of these chunks of Mars eventually crashed into the Earth and is one of the few meteorites that can be traced directly to Mars. This meteorite was rediscovered in a drawer at Purdue University in 1931 and therefore named the Lafayette Meteorite.
BioPharma Drive: Drug Pricing
NOVEMBER 18, 2024
The agency's openness to a targeted pivotal study shows it’s still willing to consider accelerated clearance for Duchenne gene therapies despite questions about their effectiveness.
LifeSciVC
NOVEMBER 18, 2024
“May you live in interesting times” – or so goes the phrase. In 1966, RFK Jr’s father famously used that quote to capture the turbulence of the times, and continued: “Like it or not, we live in interesting times. They are times of danger and uncertainty, but they are also the most creative of any time in the history of mankind.” Ironically, this is how biotech feels right now in November 2024, dealing with the shockwaves of Trump’s nomination of RFK Jr as the nation’s new health czar.
Drug Channels
NOVEMBER 15, 2024
Today’s guest post comes from Kala Bala, SVP, Enterprise Access & Data Expertise, MMIT, a Norstella company and Dinesh Kabaleeswaran, SVP, Advisory Services at MMIT, a Norstella company. The authors outline the challenges that manufacturers face when integrating internal and external datasets to build market access and commercialization strategies.
Drugs.com
NOVEMBER 15, 2024
FRIDAY, Nov. 15, 2024 -- An experimental vaccine has shown promise in protecting against the sexually transmitted disease chlamydia, researchers report.Lab mice given the vaccine were able to rapidly clear subsequent chlamydia infections, and were.
Science Daily: Pharmacology News
NOVEMBER 13, 2024
A 'one of a kind' fossil discovery could transform our understanding of how the unique brains and intelligence of modern birds evolved, one of the most enduring mysteries of vertebrate evolution.
BioPharma Drive: Drug Pricing
NOVEMBER 18, 2024
Explore solutions to reduce variability in gene expression during cell line development.
Drug Patent Watch
NOVEMBER 18, 2024
The concept of a blockbuster drug, defined as a medication generating at least $1 billion in annual sales, has long been a cornerstone of the pharmaceutical industry. However, the question arises whether a drug can achieve blockbuster status without heavily relying on U.S. sales.
addgene Blog
NOVEMBER 14, 2024
You’ve probably heard that only 2% of our genome is made of protein-coding genes, and you might be wondering what the rest of our genome could possibly be made up of. The answer is… drum roll please… non-coding RNAs! You probably didn’t see that coming, right? Non-coding RNAs (ncRNAs) are transcribed but do not encode proteins. They play important roles in many cellular and regulatory processes, but much of their functionality is yet to be unveiled as they are more difficult to functionally mani
Drugs.com
NOVEMBER 13, 2024
WEDNESDAY, Nov. 13, 2024 -- The blockbuster GLP-1 drug semaglutide (Ozempic, Wegovy) could curb drinking for people battling alcohol use disorder, helping them to avoid crises that require hospitalization, new research shows. Numerous studies had.
Science Daily: Pharmacology News
NOVEMBER 13, 2024
Researchers have developed an AI powered model that -- in 10 seconds -- can determine during surgery if any part of a cancerous brain tumor that could be removed remains.The technology, called FastGlioma, outperformed conventional methods for identifying what remains of a tumor by a wide margin. Researchers say it has the potential to change the field of neurosurgery by immediately improving comprehensive management of patients with diffuse gliomas.
BioPharma Drive: Drug Pricing
NOVEMBER 18, 2024
Revuforj is the first so-called menin inhibitor cleared in the U.S., securing FDA approval for use in adults and certain pediatric patients with an aggressive form of acute leukemia.
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