BioPharma Drive: Drug Pricing
OCTOBER 17, 2024
Vyalev’s clearance is the second victory for AbbVie in Parkinson’s this year, following an April readout for a drug acquired through its Cerevel buyout.
Drug Discovery Today
OCTOBER 15, 2024
Pioneer Group, the specialist life science infrastructure and venture-building company, welcomed 425 school children from 29 schools to eight of its sites across the UK last week to mark Ada Lovelace Day, an international celebration of the achievements of women in STEM.
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Science Daily: Pharmacology News
OCTOBER 10, 2024
Researchers developed a rating system to evaluate the plausibility of climate model simulations in the IPCC's latest report, and show that models that lead to potentially catastrophic warming are to be taken seriously.
Chemical Biology and Drug Design
OCTOBER 13, 2024
This review will provide a comprehensive analysis and outlines various state-of-the-art AI/ML techniques to the readers with their framework applications. This review also highlights the challenges in this field which need to be addressed for further successes in pharmaceutical applications. ABSTRACT The technological revolutions in computers and the advancement of high-throughput screening technologies have driven the application of artificial intelligence (AI) for faster discovery of drug mole
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Perficient: Drug Development
OCTOBER 15, 2024
This post is the third in a series of four about estimating project hours. Part 1: Sandbagging & Lowballing Part 2: Dependencies & Creep Part 3: Assumptions & Uncertainty Coming Soon: Part 4: The Emotional Conclusion In this third installment of my blog series on project estimates, let’s dive headfirst into the murky waters of assumptions and uncertainty!
Drugs.com
OCTOBER 11, 2024
FRIDAY, Oct. 11, 2024 -- Endometriosis could be linked to the health of a woman’s microbiome, a new study says. The discovery might help lead to an early test for the painful condition, and possible new treatments.A specific set of bacteria in w.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drug Channels
OCTOBER 15, 2024
A new survey of plan sponsors sheds light on their satisfaction with transparency at large and small pharmacy benefit managers (PBMs). As you will see, clients remain slightly more satisfied with the perceived transparency of smaller PBMs compared with the Big Three PBMs—CVS Caremark, Express Scripts, and Optum Rx. However, plan sponsors are dissatisfied with transparency about how both large and small PBMs make money.
BioPharma Drive: Drug Pricing
OCTOBER 14, 2024
The deal would hand Lundbeck a treatment for a series of rare brain disorders that could, by the company's estimates, become a blockbuster product.
Perficient: Drug Development
OCTOBER 11, 2024
In our ongoing Health and Life Sciences series, we’re excited to share a remarkable transformation achieved by a leading pediatric health system. This organization, renowned for its commitment to children’s health, faced challenges in scaling its outreach efforts and enhancing patient experiences. Here’s how Perficient helped revolutionize their approach using Salesforce solutions.
Drugs.com
OCTOBER 14, 2024
MONDAY, Oct. 14, 2024 -- Binge drinking at a party or club could feel great when the music's beating, but it's your heart beat that might pay the price.Researchers in Germany found that 1 in every 20 young Munich revelers developed "clinically.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Science Daily: Pharmacology News
OCTOBER 10, 2024
Scientists have discovered a low-cost method to significantly reduce this pollution from hydrogen internal combustion engines by improving the efficiency of their catalytic converters. The researchers found that infusing platinum in catalytic converters with a highly porous material called Y zeolites greatly enhances the reactions between nitrogen oxides and hydrogen, converting unhealthful nitrogen oxides into harmless nitrogen gas and water vapor.
Broad Institute
OCTOBER 15, 2024
#WhyIScience Q&A: A microbiologist and immunologist finds links between our own microbes and disease mechanisms By Ari Navetta October 15, 2024 Breadcrumb Home #WhyIScience Q&A: A microbiologist and immunologist finds links between our own microbes and disease mechanisms Eric Brown discusses finding purpose in the unpredictability of research and his personal connection to his work.
BioPharma Drive: Drug Pricing
OCTOBER 11, 2024
The French pharmaceutical giant said it’s in negotiations to sell a controlling stake of Opella to the private equity firm CD&R, in a deal that reportedly could be worth more than $16 billion.
Perficient: Drug Development
OCTOBER 16, 2024
Addressing the Talent Shortage While fears of AI-driven job displacement dominate headlines, the real crisis looming is a $8.5 trillion talent shortage projected by 2030. Much like the famous ‘invisible gorilla’ experiment, where viewers focused on counting basketball passes miss a costumed figure walking through the scene, businesses risk overlooking a crucial element: the Employee Experience (EX).
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
OCTOBER 10, 2024
THURSDAY, Oct. 10, 2024 -- After Hurricane Helene knocked out a North Carolina production plant for a major supplier of IV fluids for U.S. hospitals, officials said the federal government is reaching out internationally to help restore supply.The.
Science Daily: Pharmacology News
OCTOBER 10, 2024
A new study from The Neuro (Montreal Neurological Institute-Hospital) of McGill university, the University of Ottawa and the University of Zaragoza in Spain elaborates on bilingualism's role in cognition, showing increased efficiency of communication between brain regions.
Drug Channels
OCTOBER 11, 2024
Today’s guest post comes from Angie Franks, Chief Executive Officer of Kalderos. Angie discusses how the Maximum Fair Price provision of the Inflation Reduction Act of 2022 will challenge providers, pharmacies, and manufacturers. She explains how Kalderos’ Truzo platform could reduce duplicate claims and address compliance issues. To learn more, register for Kalderos’ October 25 webinar Cracking the MFP Code: How Flexible Technology Helps You Navigate an Evolving Landscape.
BioPharma Drive: Drug Pricing
OCTOBER 10, 2024
In a letter to Pfizer’s board, the activist investor claimed former CEO Ian Read and CFO Frank D’Amelio were pressured to abandon a Starboard-led attempt to change the company’s direction.
Drug Patent Watch
OCTOBER 14, 2024
Risk assessment plays a crucial role in the development of generic drugs, ensuring that these products meet the required standards of safety and efficacy. The Food and Drug Administration (FDA) and other regulatory bodies have implemented various measures to ensure that generic drugs are equivalent to their brand-name counterparts in terms of quality, safety, and efficacy.
Drugs.com
OCTOBER 15, 2024
TUESDAY, Oct. 15, 2024 -- People sense millisecond shifts in odor as quickly as they might spot a change in color, new research shows.The study discounts the notion that smell is a "slower" sense than sight or hearing, scientists say. "A sniff of.
Science Daily: Pharmacology News
OCTOBER 11, 2024
Astronomers have used the NASA/ESA James Webb Space Telescope (JWST) to observe the 'inside-out' growth of a galaxy in the early universe, only 700 million years after the Big Bang.
Codon
OCTOBER 13, 2024
Xander Balwit , editor-in-chief of Asimov Press, writes about a restaurant that is bullish on GMOs and other food technology for Issue 04. When one considers the millions of permutations of foods and wines to test, it is easy to see that life is too short for the formulation of dogma. — A.J. Liebling, In Between Meals The facade of Farma in San Francisco.
BioPharma Drive: Drug Pricing
OCTOBER 14, 2024
The approval of Hympavzi Friday was a dose of good news for Pfizer, which is dealing with research setbacks and a challenge from an activist investor.
addgene Blog
OCTOBER 15, 2024
We’re very excited to announce that we are expanding our viral vector service to include a Packaged on Request option. Through this expansion, scientists will be able to request an AAV composed of an AAV plasmid in the Addgene repository and their choice of five different serotypes.
Drugs.com
OCTOBER 15, 2024
TUESDAY, Oct. 15, 2024 -- Some men might have damaged sperm that will increase the risk of pregnancy complications and health problems in newborns, a new study finds.DNA defects in sperm can double the risk of preeclampsia, a dangerous pregnancy.
Science Daily: Pharmacology News
OCTOBER 11, 2024
Scientists analyzed hairs extracted from the broken teeth of two 19th century 'man-eater' lions. Their analysis revealed DNA from giraffe, human, oryx, waterbuck, wildebeest and zebra as prey, along with hairs that originated from the lions.
Drug Patent Watch
OCTOBER 17, 2024
Regulatory Considerations for Biosimilar Analytical Similarity Assessments Biosimilars, or follow-on biologics, are biopharmaceuticals that are highly similar to an already approved biological product.
BioPharma Drive: Drug Pricing
OCTOBER 16, 2024
The results provide the first clinical evidence of RNA editing, a burgeoning field that's drawn interest from biotechs and pharmaceutical companies alike.
Covalent Modifiers
OCTOBER 15, 2024
Xingyu Ma, Manyi Xu, Fengge Wang, Tingting Hu, Xinyuan Chena and Chong-Jing Zhang Chem. Commun. , 2024 DOI [link] Reversible covalent electrophiles with the advantages of both reversible and covalent interactions receive much attention in the fields of chemical biology and medicinal chemistry. Here, we report two electron-deficient olefins activated by amide and ester, amide-substituted acrylamide and methyl ester-substituted acrylamide, targeting thiols in a reversible covalent manner.
Drugs.com
OCTOBER 14, 2024
MONDAY, Oct. 14, 2024 -- About 6.5 million “Near Dual” seniors are struggling to afford long-term care as they grow older and more frail, a new study warns.“Near Dual” seniors are those who are eligible for Medicare but are only at the cusp of eligi.
Science Daily: Pharmacology News
OCTOBER 11, 2024
A new technique enables makers to finely tune the color, shade, and texture of 3D-printed objects using only one material. The method is faster and uses less material than other approaches.
Drug Patent Watch
OCTOBER 10, 2024
China has emerged as a significant player in the global generic drug active pharmaceutical ingredient (API) market. The country’s vast production capacity, low costs, and strategic location have made it an attractive destination for pharmaceutical companies seeking to source APIs.
BioPharma Drive: Drug Pricing
OCTOBER 17, 2024
The restructuring, which follows clinical setbacks in Alzheimer’s, Parkinson’s and tremor, will also involve the departure of five senior executives.
Reprocell
OCTOBER 17, 2024
Over the years, REPROCELL USA has worked on several projects involving blood and blood components. The company has experience with collection, biobanking, nucleic acid extraction, among other services. Blood derived plasma and serum are two materials which are useful in clinical/experimental settings and have been at the forefront of many REPROCELL USA activities.
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