Broad Institute

JANUARY 6, 2025

Researchers devise new way to target and correct disease-related proteins By Leah Eisenstadt January 6, 2025 Breadcrumb Home Researchers devise new way to target and correct disease-related proteins Broad scientists built a diverse library of compounds and found one that stabilizes a dysfunctional protein in Crohns disease, demonstrating their librarys potential to uncover new therapeutic strategies.

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BioPharma Drive: Drug Pricing

JANUARY 7, 2025

Denali’s medicine and a similar one from Calico Life Sciences and AbbVie were not much different than a placebo, bringing the tally of failed drugs in the innovative “Healey platform trial” to seven.

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Trials Science Drugs 130

Science Daily: Pharmacology News

JANUARY 2, 2025

A research team has developed a method for extracting gold from electronics waste, then using the recovered precious metal as a catalyst for converting carbon dioxide (CO2), a greenhouse gas, to organic materials.

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Drugs.com

JANUARY 6, 2025

MONDAY, Jan. 6, 2025 -- Rates of whooping cough in the U.S. continue to climb, according to data from the US Centers for Disease Control (CDC).Over 32,000 cases reported have been reported as of mid-December -- about six times more than there were.

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Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

Chemical Biology and Drug Design

JANUARY 5, 2025

5(4-Hydroxyphenyl)-2-(N-Phenyl amino)-1,3,4-Oxadiazole (Hppo) can considered as a versatile agent in designing novel pharmaceuticals. ABSTRACT Oxadiazole compounds are of great interest because they have a range of biological activities ranging from antioxidants to anticancer agents. Against this background, we wanted to demonstrate the antioxidant, enzyme inhibitory, and anticancer effects of 5(4-hydroxyphenyl)-2-(N-phenylamino)-1,3,4-oxadiazole (Hppo).

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Broad Institute

JANUARY 6, 2025

Feng Zhang awarded the National Medal of Technology and Innovation By Corie Lok January 6, 2025 Breadcrumb Home Feng Zhang awarded the National Medal of Technology and Innovation Zhang and 22 other individuals received the USs highest honors for science and technology. By Broad Communications January 6, 2025 Credit: Ryan K. Morris Feng Zhang receives the National Medal of Technology and Innovation at the White House from Arati Prabhakar (left), director of the White House Office of Science and T

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BioPharma Drive: Drug Pricing

JANUARY 6, 2025

The startup is developing a kind of macrocyles, which share strengths of both small molecules and biologics, as oral medicines against “validated blockbuster biologic targets.

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Small Molecule 120

Drugs.com

JANUARY 3, 2025

FRIDAY, Jan. 3, 2025 -- If you've picked up a bag of Marketside Broccoli Florets from Walmart recently, check your fridge or freezer. The company has issued a recall of the 12-ounce bags in 20 states after testing uncovered listeria bacteria in one.

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Codon

JANUARY 5, 2025

Today we launch Issue 05 of Asimov Press. Read our full Editors’ Note and preview upcoming articles on our website. Thanks for reading! Edwin Cohn, a temperamental and entrepreneurial protein chemist working at Harvard University in the early 1900s, is perhaps one of the most underrated translational scientists of all time. In 1940, with the likelihood of America’s involvement in World War II steadily rising, the U.S. military approached Cohn about developing medical products from bl

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Plenge Gen

JANUARY 7, 2025

When I last wrote about AI on this blog three years ago, I spoke of it being a tool with the potential to transform scientific discovery, but the application I described was primarily theoretical. For AI to be a meaningful tool in R&D, I argued, we needed better sources of truth better data sets that AI tools could query and learn from over time and technology capable of integrating multiples steps into a semi-automated system.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Science Daily: Pharmacology News

JANUARY 3, 2025

Scientists recently discovered that the giant 'conveyer belt' currents that push star-forged material out of our galaxy and pull it back in can also transport carbon atoms. That means that a good deal of the carbon here on Earth, including the carbon in our bodies, likely left the galaxy at some point!

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BioPharma Drive: Drug Pricing

JANUARY 2, 2025

Expected readouts in diabetes, cancer and depression headline a series of study results that could help the biotechnology sector regain its footing after a shaky year.

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Clinical Trials Trials 108

Drugs.com

JANUARY 2, 2025

THURSDAY, Jan. 2, 2024 -- Weight loss tops many folks list of New Years resolutions, and lots of people are turning to cutting-edge weight-loss drugs like Ozempic to help them drop excess pounds.These drugs, called glucagon-like peptide-1 receptor.

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Perficient: Drug Development

JANUARY 6, 2025

Welcome to our ongoing series on Universal Design for Healthcare! In this segment, well explore the importance of Visual Disabilities in Healthcare. The healthcare sector is witnessing an evolutionary shift towards inclusivity and accessibility. At the heart of this transformation lies universal designa principle that advocates for the creation of environments and products to be usable by all people, to the greatest extent possible, without the need for adaptation or specialized design.

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Crown Bioscience

JANUARY 8, 2025

How To Choose and Use Drug Resistance Models Drug resistance remains one of the most pressing challenges in cancer drug development, as 90% of cancer deaths worldwide can be attributed to resistance and the drug ineffectiveness associated with it. This ongoing issue can take one of two forms: intrinsic resistance, where cancer cells show inherent insensitivity to therapies from the outset, and required resistance, which develops during treatment as cancer cells adapt and evolve to survive exposu

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Science Daily: Pharmacology News

JANUARY 3, 2025

Interactions with friends and family may keep us healthy because they boost our immune system and reduce our risk of diseases such as heart disease, stroke and type 2 diabetes, new research suggests. Researchers drew this conclusion after studying proteins from blood samples taken from over 42,000 adults recruited to the UK Biobank.

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BioPharma Drive: Drug Pricing

JANUARY 7, 2025

The startup, which has already raised more than half a billion dollars, released Phase 2 results that could position its drug as a future threat to weight loss medicines from Novo Nordisk and Eli Lilly.

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Drugs 105

Drugs.com

JANUARY 2, 2025

THURSDAY, Jan. 2, 2025 -- Considering a New Year’s resolution to quit smoking? New research might provide all the motivation you need: Each cigarette could shorten your life by up to 22 minutes, researchers say. The findings, published Dec.

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Research 105

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Covalent Modifiers

JANUARY 7, 2025

Tomonori Tamura and Itaru Hamachi Accounts of Chemical Research 2025 58 (1), 87-100 DOI: 10.1021/acs.accounts.4c00628 Selective chemical modification of endogenous proteins in living systems with synthetic small molecular probes is a central challenge in chemical biology. Such modification has a variety of applications important for biological and pharmaceutical research, including protein visualization, protein functionalization, proteome-wide profiling of enzyme activity, and irreversible inhi

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Perficient: Drug Development

JANUARY 9, 2025

The Evolution of Java and Its Significance in Enterprise Applications Java has been the go-to language for enterprise software development for decades, offering a solid and reliable platform for building scalable applications. Over the years, it has evolved with each new version. Security Enhancements of Java 17 Long-Term Support Java 17, being a Long-Term Support (LTS) release, is a strategic choice for enterprises using MuleSoft.

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Science Daily: Pharmacology News

JANUARY 2, 2025

Viral infections may play a role in Alzheimer's disease.

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BioPharma Drive: Drug Pricing

JANUARY 8, 2025

The regulator is requiring labeling that warns of Guillan-Barré syndrome, although it said data don’t prove a causal link and affirmed the shots’ benefit outweighs their risks.

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Drugs.com

JANUARY 2, 2025

THURSDAY, Jan. 2, 2025 -- A Canadian teen's severe bird flu infection has highlighted growing concerns about the H5N1 virus, commonly known as bird flu, which has seen a steady rise in human cases across the U.S. According to a news release, the.

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Fierce BioTech

JANUARY 3, 2025

Optimizing Formulation Strategies for Poorly Soluble Compounds: Insights into Bioavailability Enhancement and Accelerated Development dwunderlin Fri, 01/03/2025 - 15:54 Wed, 02/19/2025 - 11:00 Resource Type Webinar Feng Zhang, Ph.D. Hong Li, Ph.D. Duration 60 Minutes With 70% of small molecule drug candidates classified as poorly soluble (BCS Class II and IV), achieving adequate absorption in the gastrointestinal (GI) tract remains a critical challenge in drug development.

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Small Molecule Drug Development Drugs 52

Perficient: Drug Development

JANUARY 9, 2025

MuleSoft and Boomi are two popular businesses that provide reliable solutions for integrating devices, data, and apps in the constantly changing field of enterprise integration. Every platform has distinct characteristics and advantages that make it appropriate for various company requirements. To help you make a wise choice, we will examine the key features and elements of Boomi and MuleSoft in this blog.

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Science Daily: Pharmacology News

JANUARY 3, 2025

Antibodies that bind to a previously untargeted portion of the malaria parasite could lead to new monoclonal antibody treatments and vaccines for malaria.

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BioPharma Drive: Drug Pricing

JANUARY 6, 2025

Esperion CEO Sheldon Koenig reflects on personal challenges and advancing innovative heart therapies.

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Pharma Companies Therapies 70

Drugs.com

JANUARY 6, 2025

MONDAY, Jan 6, 2025 -- Turns out, starting physical therapy earlier after a concussion may significantly improve recovery outcomes.A new study published recently in the Physical Therapy & Rehabilitation Journal followed just over 200 adults.

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Crucial Data Solutions

JANUARY 8, 2025

RENO, NV, UNITED STATES, January 8, 2025 /EINPresswire.com/ — Crucial Data Solutions (CDS), a leader in eClinical technology and a. The post Crucial Data Solutions Begins 2025 with AI Breakthroughs and Leadership Momentum appeared first on Crucial Data Solutions.

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Fierce BioTech

JANUARY 3, 2025

Innovations in aseptic processing for container closure systems dwunderlin Fri, 01/03/2025 - 14:26 Wed, 02/12/2025 - 10:00 Resource Type Webinar Jim Thompson Julian Petersen Duration 60 Minutes The pharmaceutical landscape is shifting from blockbuster drugs to personalized treatments, driving the need for innovative container closure systems. This joint webinar presentation by West and Groninger, explores the unique challenges of Cell and Gene Therapies, mRNA LNP therapeutics particularly regard

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Science Daily: Pharmacology News

JANUARY 3, 2025

Bioengineers have developed a new construction kit for building custom sense-and-respond circuits in human cells. The research could revolutionize therapies for complex conditions like autoimmune disease and cancer.

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BioPharma Drive: Drug Pricing

JANUARY 2, 2025

The well-funded biotech lost most of its value after its drug flunked a late-stage trial. One analyst described the results as a “worst-case scenario for the program.

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Drugs Trials 67

Drugs.com

JANUARY 2, 2025

THURSDAY, Jan. 2, 2024 -- Not sure what’s causing your child’s asthma? A new quick-and-easy nasal swab test for kids can diagnose the specific immune system drivers behind their asthma, potentially opening the door to better treatments.

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