NIOSH Science Blog: Drugs

SEPTEMBER 25, 2023

2 In 2001, only about 1 out of every 7 U.S. The center encourages workplaces to integrate workers of all ages, and it gives useful resources on age-related issues for businesses and industries. Why It Matters Trends in population aging1 are expected to profoundly affect the workforce for years to come.2

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SCIENMAG: Medicine & Health

JUNE 22, 2023

Lehigh’s IAC was established in 2001 as part of the DOE’s nationwide Industrial Assessment Center Program to reduce energy and waste and enhance productivity for manufacturing plants in Pennsylvania, New […] Department of Energy (DOE).

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Production 79

NIOSH Science Blog: Drugs

AUGUST 2, 2023

Based on data from the OHBWC claims database, the researchers analyzed a comprehensive set of injury claims filed by firefighters from 2001-2017. The objective was to characterize the demographics of firefighter claimants, most frequent injury events, common diagnoses, and

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Research 68

LifeSciVC

NOVEMBER 30, 2023

As a historical comparison, in the post-Genomics-Bubble aftermath from 2001-2003, the public biotech sector only shrank 7% despite similarly loud calls for consolidation, according to data in E&Y Reports from that time. So why has it been so hard to drive consolidating deals or liquidations, either now or in the post-2001 aftermath?

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DrugBaron

JANUARY 8, 2021

But before doing so, its worth reading a few paragraphs from a Commentary on gene therapy that DrugBaron wrote in 2001, marking the first publication of the completed human genome sequence, just to remind us that the central flaw in the Sarepta story was well-known two decades ago.

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The Pharma Data

DECEMBER 23, 2020

23 2020 — From 2001 to 2016, out-of-pocket costs of evaluation and management (E/M) services and common diagnostic tests increased for neurology patients, according to a study published online Dec. WEDNESDAY, Dec. 23 in Neurology. Data were included for 3,724,342 patients. percent, respectively).

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thought leadership

JULY 2, 2024

In this respect, a clinical trial with a GMO must also comply with either the contained use Directive (2009/41/EC) or the deliberate release Directive (2001/18/EC). The Directive that actually applies to a clinical trial with GMOs is dependent upon the individual Member States (MS) (see Figure 1).

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The Pharma Data

OCTOBER 19, 2020

Intellia has received approval to launch their Phase I trial of NTLA-2001 in hereditary ATTR. Their NTLA-2001 candidate uses their proprietary non-viral lipid nanoparticle platform, which will deliver this CRISPR/Cas9-based therapy. hATTR is an inherited DNA mutation of the TTR gene.

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Common Sense for Drug Policy Blog

DECEMBER 17, 2023

In Portugal, despite being legal since 2001, the first DCR only came into reality in 2019 by the initiative of the City Council of Lisbon." Portugal Opened Its First Safe Consumption Site In 2019 "Drug consumption rooms (DCR) are in place for more than three decades in Europe and have been proven to be effective as a public health response.

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The Pharma Data

DECEMBER 24, 2020

For example, the percentage of patients who had out-of-pocket payments for MRIs rose from 24% in 2001 to 70% in 2016. The number of patients enrolled in high-deductible plans rose from zero in 2001 to 11% in 2016, according to the study. The researchers also found an increase in patients who paid out-of-pocket costs for tests.

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Research 52

Broad Institute

AUGUST 11, 2023

In 2001, Donnelly joined the Whitehead Institute/MIT Center for Genome Research, now part of the Broad Institute, where she was in charge of the center’s sponsored research portfolio and helped establish and maintain the first high-throughput Specialized Service Facilities (SSFs).

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FDA Law Blog: Biosimilars

MAY 3, 2023

Before joining HP&M in 2001, Mr. Houck conducted numerous scheduled cyclic and targeted inspections and investigations as a DEA Diversion Investigator in the field for ten years. Registrants are far from powerless when DEA investigators inspect their controlled substance operations.

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International Drugs 52

The Pharma Data

APRIL 10, 2021

Prior to this, Dr. Freire served as President and Chief Executive Officer of the Global Alliance for TB Drug Development from 2001 to 2008 and Director of the Office of Technology Transfer at the National Institutes of Health from 1995 to 2001. Dr. Freire also serves as a director of Alexandria Real Estate Equities, Inc.,

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Government Science Disease International 52

The Pharma Data

OCTOBER 23, 2020

A pharmaceutical consultant at RMJ Consulting from 2008 to 2009, he found success as the vice president of global quality at Wyeth/FDAH from 2005 to 2008, the director of the Corporate Quality Center of Excellence of Abbott from 2001 to 2005, the director of corporate quality technology at Alcon Laboratories, Inc.,

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Pharmaceuticals International Engineering Science 52

FDA Law Blog: Biosimilars

SEPTEMBER 12, 2023

In this webinar you’ll learn: How employees diverted controlled substances — their methods are constantly evolving What red flags were missed DEA inspection priorities Safeguards to minimize internal diversion Best practices for maximizing diversion detection Mr. Houck was a DEA Diversion Investigator for 15 years prior to joining HPM in 2001.

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Hospitals Pharmacy Compliance Government 49

The Pharma Data

JANUARY 27, 2021

years) participating in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (1993 to 2001). Loomans-Kropp, Ph.D., The analysis included 139,896 individuals (mean age, 66.4 The researchers found that aspirin use was not associated with the incidence of any studied cancer type.

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Trials Research 52

Common Sense for Drug Policy Blog

JANUARY 5, 2024

Historians trace the use of coffee back to the fifth century, in the Sufi monasteries of Mocha, now known as Yemen (Weinberg and Bealer 2001 ). Studies in sports medicine attest to caffeine’s positive effects in adults, including increased endurance and strength, improved reaction time, and delayed fatigue (Graham 2001 ; Sökmen et al.

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Pharmacy Regulations Production Marketing 52

The Pharma Data

NOVEMBER 30, 2020

A total of 2,350,330 singleton pregnancies were identified from 2001 to 2012, including 4,058 singleton pregnancies among psoriasis patients. Yu-Heui Huang, M.D., The researchers found that the adjusted odds ratios (95 percent confidence intervals) were 1.57 (1.31 to 1.89), 1.5 to 1.75), and 1.57 (1.36

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Pharmaceuticals Research 52

The Pharma Data

NOVEMBER 23, 2020

Dietary information was collected at baseline (1993 to 2001) and follow-up (around 2010). Tong, Ph.D., from the University of Oxford in the United Kingdom, and colleagues conducted a prospective study to examine differences in fracture risks between vegetarians, vegans, and nonvegetarians.

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Research 52

LifeSciVC

DECEMBER 5, 2024

In 1999-2001, Atlas raised three funds in quick sequence, aggregating over $2B of “early stage” multi-sector venture capital and aimed to scale the business to global proportions; we opened nine offices on several continents, had dozens of partners (and layers of partners), and invested in every area under the sun.

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Marketing RNA Science Drugs 76

PLOS: DNA Science

MARCH 21, 2024

Gene therapy had progressed faster in Europe over the previous decade than in the US, due to delays in clinical trials in the wake of the death of 18-year-old Jesse Gelsinger in a trial to treat a urea cycle disorder, and then after five boys developed leukemia, with one death, in a trial for a form of severe combined immune deficiency in 2001.

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The Pharma Data

OCTOBER 21, 2020

from the Karolinska Institutet in Stockholm, and colleagues performed a cohort study involving 3,016,307 Swedish women who participated in cervical screening during 2001 to 2012 to examine the risk for injuries during the diagnosis of cervical cancer and its precursor lesions. Qing Shen, Ph.D.,

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Hospitals Research 52

PLOS: DNA Science

JULY 27, 2023

which spit out information guiding the trimming of tumors in real time, a bit reminiscent of its ancestor Hal the computer from 2001: A Space Odyssey. And then in 2001 came us. Duke University neurosurgeon Oren Gottfried voiced 2.0, I recently recounted the history of human genome sequencing, here at DNA Science.

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FDA Law Blog: Biosimilars

SEPTEMBER 26, 2023

In this webinar you’ll learn: How employees diverted controlled substances — their methods are constantly evolving What red flags were missed DEA inspection priorities Safeguards to minimize internal diversion Best practices for maximizing diversion detection Mr. Houck was a DEA Diversion Investigator for 15 years prior to joining HPM in 2001.

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Hospitals Pharmacy Compliance Government 45

ACTO

OCTOBER 22, 2024

We’ve come a long way since Stanley Kubrick’s 2001: A Space Odyssey. When you think about Artificial Intelligence (AI), what image comes up? Or this (if you’re a movie buff of a certain age)? Promising recent developments include Eli Lilly and Company appointing its first Chief AI Officer.

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Science Regulations FDA Compliance 52

National Institute on Drug Abuse: Nora's Blog

AUGUST 28, 2024

Until 2001, deaths from overdose among Black people were consistently much higher than in white people, yet in that era, the drug problem in Black communities was framed as a problem of crime and deviance, not legitimized through a lens like despair.

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Treatment Research Disease Drugs 110

The Pharma Data

JANUARY 20, 2021

children and teens with type 2 diabetes increased by 30% between 2001 and 2009, with cases growing among youth aged 10 and older. . “The condition occurs when the body stops making the hormone insulin,” Eapen explained in a Hackensack Meridian Health news release. The number of U.S. Symptoms.

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Drug Target Review

JULY 6, 2023

USA 98, 8554-8559 (2001) Zhang G, Zhang J, Gao Y, et al. Available from: [link] Sakamoto KM et al. Protacs: Chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubuquitination and degradation. Strategies for targeting UNDRUGGABLE targets. Expert Opinion on Drug Discovery. 2021;17(1):55–69.

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Targeted Protein Degradation Small Molecule Clinical Trials Science 98

PLOS: DNA Science

AUGUST 17, 2023

Consider the role of mtDNA in the days and weeks following September 11, 2001. Forensic analyses using mtDNA has impacted criminal cases and identifying human remains from plane crashes, terrorist attacks, wars, and natural disasters like tsunamis, volcanic eruptions, floods, and fires.

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DNA Disease Science Research 98

NIH Director's Blog: Drug Development

OCTOBER 11, 2022

The first such call came in 2001, when Sharpless got the news that he was a co-winner of the Nobel Prize in Chemistry for his discovery of asymmetric catalytic reactions. 2001, 40 (11), 2004–2021 [2] A stepwise huisgen cycloaddition process: Copper(I)-catalyzed regioselective “Llgation” of azides and terminal alkynes.

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Research Small Molecule Science Clinical Research 52

Common Sense for Drug Policy Blog

DECEMBER 20, 2023

In 2001, both the decriminalization of low-level possession and use of illicit drugs and the Decree-law 183, regulating harm reduction responses, came into effect. DCRs are among the harm reduction measures detailed.

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Government Regulations Drugs 40

FDA Law Blog: Biosimilars

MAY 22, 2023

Before joining HP&M in 2001, Mr. Houck conducted numerous scheduled cyclic and targeted inspections and investigations as a DEA Diversion Investigator in the field for ten years. Registrants are far from powerless when DEA investigators inspect their controlled substance operations.

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International Drugs 40

Common Sense for Drug Policy Blog

JULY 8, 2023

Hughes & Stevens, for example, have compared Portugal to neighbouring countries that did not introduce significant reforms in the period 2001–11 and showed that Portugal is the only country that exhibited a decline in hazardous drug use [ 8 ]. "Nevertheless, it is undeniable that the system brought positive results.

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Drugs International Treatment Disease 52

NIH Director's Blog: Drug Discovery

MAY 9, 2013

2001 Dec 1;15(23):3217-29. 2013 Apr 25;496(7446):443-4. [3] 3] vhnf1, the MODY5 and familial GCKD-associated gene, regulates regional specification of the zebrafish gut, pronephros, and hindbrain. Sun Z, Hopkins N.

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Disease Science International Regulations 52

Advarra

JUNE 30, 2023

Background In 2001, Medicare released the national coverage determination (NCD) 310.1. However, a year has passed with no further updates on this letter or Medicaid beneficiaries enrolling in clinical trials. How can your institution best prepare for this change and what can you expect for the future?

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The Pharma Data

SEPTEMBER 8, 2021

For example, in 2001 with anthrax and 2003 with SARS-CoV1, TIB Molbiol demonstrated their ability to develop PCR assays for the detection of new pathogens within days.

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Virus Assay Development Disease Research 52

PPD

MAY 11, 2023

Emphasizing Safety and Ethics, Reducing Patient Burden Since 2001, the European Directive 2001/20/EC has provided foundational guidance for research involving children to ensure the highest level of safety and ethics.

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