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Targeted protein degradation: turning undruggable targets into druggable targets

Drug Target Review

Programme : the leader programme ASP3082 entered the clinical trial phase last year, and multiple forum programmes are currently under investigation in the light research phase. USA 98, 8554-8559 (2001) Zhang G, Zhang J, Gao Y, et al. ASP3082 experienced an expedited R&D process as it was targeting the KRAS G12D mutation.

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Women in Stem with Dr Sara Sangha

Drug Target Review

Since joining Allergan Aesthetics in 2001, my role in medical affairs has always focused, in one way or another, on supporting the journey of a drug/device from bench to bedside. One of the biggest obstacles I faced early in my career was the perception that women often quit their career to achieve a work-life balance.

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Chipscreen and HISUN reach a strategic cooperation

The Pharma Data

As the world’s first PPAR pan agonist that completed two confirmatory phase III clinical trials, Chiglitazar Sodium has shown significant and long-lasting hypoglycemic effects in a series of clinical studies, as well as other comprehensive effects including significant insulin sensitization and blood lipid regulation.

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Allecra Therapeutics and Shanghai Haini Pharmaceutical Announce Exclusive Licensing Agreement for Cefepime/enmetazobactam for Greater China

The Pharma Data

Cefepime/enmetazobactam will be a welcome addition to the tools that doctors have to help their patients, and we look forward to introducing this antibiotic to hospitals and achieving a win-win collaboration.”. Shanghai Haini) was founded in 2001. and EU based on these results.

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Raising Welfare for Lab Rodents

Codon

According to Weary, the “recognition that the animal is an individual that has a life beyond this particular trial” positively influences their treatment at the hands of researchers. In an effort to continue this cycle, researchers at UBC also try to get their animals adopted at the end of their studies.

Research 124
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The Dangers of Mirrored Life

Codon

7 During the few years that thalidomide was available on the market — and before Australian doctor William McBride warned of its consequences in a letter published in The Lancet in 1961 — it affected more than 10,000 babies, killing about half of them within months after birth.

DNA 104
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The Pursuit of Parenthood

Codon

After six years of such trials, Rock marveled as fertilized eggs formed zygotes and entered the cleavage stage of embryonic development. Various techniques for using abnormal sperm in fertilization were trialed through the late 1980s, but by 1995, the clear winner was intracytoplasmic sperm injection (ICSI). Since IVF in the U.S.