PLOS: DNA Science

JUNE 1, 2023

DEB has been a candidate for a gene therapy since 2002. This DNA Science post from 2018 traces the history of the efforts. Peter Marinkovich, MD, director of the Blistering Disease Clinic at Stanford Health Care, calls DEB a devastating disease. RDEB is inherited from two carrier parents. Primary investigator M.

FDA Approval 52

FDA Approval Therapies FDA Disease 52

Drug Discovery World

JANUARY 23, 2023

Further innovative research in the fields of developmental biology and bioengineering have since advanced and refined our understanding of iPSCs, allowing researchers intricate control over iPSC differentiation with the potential to repair and replace diseased and damaged tissues.

Therapies 130

Therapies DNA Engineering RNA 130

New Drug Approvals

JANUARY 9, 2024

The present invention is directed to methods of preparation of compound of formula (I) that is useful for inhibiting Cyclin-dependent kinase 7 (CDK7) and for treating diseases or disorders mediated thereby. CDK7 also plays a role in transcription and possibly in DNA repair. 8, 3527-3538, 2002). Aug 26;78(4):713- 24, 1994).

Production 62

Production DNA RNA Regulations 62

PLOS: DNA Science

JULY 11, 2024

In the classic film Jurassic Park (JP) from 1993, disasters unfurl at a theme park populated with dinosaurs cloned from reptile DNA in mosquitoes fossilized in amber, with modern frog DNA filling in gaps. The animals were cloned from DNA in bits of preserved ear bones, and doctored a bit. percent of our DNA sequence with chimps?

DNA 52

DNA Science Doctors Engineering 52

PLOS: DNA Science

MAY 25, 2023

Myotonic dystrophy type 1 (DM1), an inherited disease affecting muscles, was one of the first described “expanding repeat” disorders. In these 50 or so conditions, symptoms may appear earlier and worsen from generation to generation, as the mutant gene grows, adding copies of a 3- or 4-base DNA sequence.

Treatment 52

Treatment DNA RNA Clinical Trials 52

BMG Labtech

MARCH 8, 2023

In biology , scientific research on cell metabolism focuses on different topics such as understanding the fundamental metabolic processes, metabolic changes and their role in diseases (including cancer cell and tumor metabolism), the development of therapies, the identification of unknown metabolic processes and metabolites, etc.

Molecular Biology 52

Molecular Biology Production Cell Based Assays Disease 52

Codon

MARCH 12, 2023

“The recombinant DNA breakthrough has provided us with a new and powerful approach to the questions that have intrigued and plagued man for centuries. The central dogma is often depicted as DNA→RNA→protein, but it’s much more: A biophysical marvel inside the smallest of vessels. Biology is a Burrito. 6 of 31.

DNA 52

DNA Engineering RNA Therapies 52

Codon

MARCH 24, 2024

Water accounts for 70 percent of a bacterium by mass; the other 30 percent includes everything else: proteins, RNA, DNA, lipids, and so on. Experiments around using genetically modified organisms to produce proteins have been taking place since the earliest days of the recombinant DNA revolution.

Engineering 87

Engineering Vaccine Production RNA 87

Codon

AUGUST 10, 2023

Cell (2002). Nature Genetics (2002). Drug Discovery Today: Disease Models (2008). Technologies DNA Sequencing →DNA sequencing at 40: past, present and future , by Shendure J. Link DNA Cost and Productivity Data, aka "Carlson Curves" , by Carlson R. Scitable, by Nature Education. & Reinberg D.

DNA 93

DNA Cell Biology Molecular Biology Engineering 93

Codon

AUGUST 10, 2023

Cell (2002). Nature Genetics (2002). Drug Discovery Today: Disease Models (2008). Technologies DNA Sequencing →DNA sequencing at 40: past, present and future , by Shendure J. Link DNA Cost and Productivity Data, aka "Carlson Curves" , by Carlson R. . & Reinberg D. Nature Methods (2013).

DNA 52

DNA Cell Biology Engineering Molecular Biology 52