Drug Discovery World

JANUARY 23, 2023

Base editing uses a guide RNA in partnership with a nickase version of Cas9, mutated to cut only a single strand of DNA, along with a deaminase enzyme to enable alteration of a single nucleotide 23,24. doi:10.1182/blood-2002-05-1483. Development and characterization of a modular CRISPR and RNA aptamer mediated base editing system.

Therapies 130

Therapies DNA Engineering RNA 130

Codon

MARCH 12, 2023

But the technologies devised in the process of trying may revolutionize other areas of science, especially reproductive biology. Biology is a Burrito. The central dogma is often depicted as DNA→RNA→protein, but it’s much more: A biophysical marvel inside the smallest of vessels. 15 of 31.

DNA 52

DNA Engineering RNA Therapies 52

Codon

AUGUST 10, 2023

Journal of Molecular Biology (1961). Cell (2002). Nature Genetics (2002). Nature Reviews Molecular Cell Biology (2008). Link Mathematical modeling and synthetic biology , by Chandran D. Link Molecular Cloning Techniques , by AddGene. Molecular Biology of the Cell, 4th Edition.

DNA 93

DNA Cell Biology Molecular Biology Engineering 93

Codon

AUGUST 10, 2023

Journal of Molecular Biology (1961). Cell (2002). Nature Genetics (2002). Nature Reviews Molecular Cell Biology (2008). Link (Golden Gate assembly) Other Basic Methods & Cloning →Basic Methods in Cellular and Molecular Biology , by multiple authors. Molecular Systems Biology (2008).

DNA 52

DNA Cell Biology Engineering Molecular Biology 52