Re-assessing the risks of drug-induced arrhythmias during drug discovery
Drug Discovery World
AUGUST 15, 2023
However, many other drugs exhibit a more complex multichannel pharmacology 7 , which is much harder to interpret and cannot be easily modelled by screening against a single ion channel. Figure 3: Electrograms (left panel) are recorded at increasingly short intervals between the stimuli (the ‘S1S2 interval’). 96(5): 549-558. Tisdale et al.
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