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CAR-NK cells: promising for cancer therapy

Drug Target Review

Only three of the CAR-NK studies were for the treatment of solid tumours. The non-CAR-NK studies showed very good safety data when compared to neurological and cytokine storm responses reported for CAR-T cell trials. Three patients were treated with 2-6 doses of 2×10 7 to 2×10 9 cells.

Therapies 118
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On Prions and Protein Design

Codon

However, despite rapid progress in the field of protein biology, “core” features of these molecular machines — how they fold, how they change shape, and how simple strings of amino acids can yield forms of incredible complexity — remain unknown. Proteins designed by David Baker’s laboratory, 2003-2023.

RNA 86
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New advances in hormone replacement therapy set to transform care

Drug Target Review

Hormone replacement therapy (HRT) for low hormone levels is one of the oldest treatments utilised in Western medicine and can be traced back centuries. 2 Sex hormone replacement also gained in popularity, notably starting in 1940, when conjugated equine oestrogen was approved for the treatment of postmenopausal women. Ann Intern Med.

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Levers for Biological Progress

Codon

Amodei also imagines the ways AI could accelerate biological research and yield miraculous cures in the 21st century; everything from the prevention and treatment of nearly all infectious and inherited diseases to the elimination of most cancers. A first draft was published in 2003; it was a patchwork of sequenced DNA from multiple people.

DNA 120