Re-assessing the risks of drug-induced arrhythmias during drug discovery
Drug Discovery World
AUGUST 15, 2023
Manual patch-clamping of single cells has become a mainstay of functional electrophysiology, often used to follow up after novel hit compounds are identified by non-functional fluorescence or ligand binding methods, which are considerably higher in their throughput. Current Pharmaceutical Design, 12(4): 397- 406 Rassmussen et al.
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