Remove 2003 Remove Compound Screening Remove Therapies Remove Trials
article thumbnail

Re-assessing the risks of drug-induced arrhythmias during drug discovery

Drug Discovery World

Specifically, we propose the hypothesis that whole-heart pacing studies are more likely than standard reductionist methods to recapitulate the biology of cardiac therapy (or toxicity) in human patients and hence have higher predictive validity than conventional methods. Clinical Pharmacology & Therapeutics. 96(5): 549-558. Tisdale et al.

Drugs 130