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Eclectic Genomics: Cat Flu, Dolphin Adaptation to Climate Change, Predicting Cancer, and Diagnosing Rare Disease

PLOS: DNA Science

Genomics applies to all species, revealing evolution in action, because we all use the same genetic code – that is, the correspondence between DNA sequences and the amino acid sequences of proteins. Cats and Bird Flu Comparing DNA sequences is a little like linguistic research that connects languages.

Disease 92
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China’s National Medical Products Administration approves Benlysta (belimumab) for adult patients with active lupus nephritis

The Pharma Data

positive anti-double-stranded DNA and low complement, and an objective assessment of overall disease activity using SELENA-SLEDAI score ? It is also the first biologic in China’s 2021 National Reimbursement Drug List for paediatric SLE. 8) in combination with standard of care. About the BLISS-LN trial. About lupus.

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Antibody-drug conjugates payloads: then, now and next

Drug Target Review

Antibody-drug conjugates (ADCs) have been a groundbreaking approach to cancer treatment with their ability to deliver cytotoxic drugs directly to diseased cells while sparing healthy tissues. 1 However, efforts proved less effective than the original drugs, owing mostly to insufficient toxicity against cancer cells.

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Welcome to Asimov Press

Codon

Recombinant DNA technologies were invented in the 1970s. Gene-editing methods, polymerase chain reaction, and the first human drug made from engineered microbes all debuted in the 1980s. A first draft of the human genome was completed in 2003. We’re particularly fond of Why We Didn’t Get a Malaria Vaccine Sooner.