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DNA, proteins, polysaccharides, etc.). They are strongly oxidizing and, at high concentrations, are deleterious to cells damaging DNA, proteins and lipids, and eventually leading to cell death. Ensign SA, Revisiting the glyoxylate cycle: alternate pathways for microbial acetate assimilation, Molecular Microbiology. PMC 1456893.
Molecularbiology, as the field came to be called 3 , pushed biology from an object of study, driven forward by gentleman scientists and precocious country clergymen, into a tool with which to solve urgent problems. Recombinant DNA technologies were invented in the 1970s.
By Matthew Cobb The Central Dogma is a linchpin for understanding how cells work, and yet it is one of the most widely misunderstood concepts in molecularbiology. Many students are taught that the Central Dogma is simply “DNA → RNA → protein.”
I’ve chosen these two because I think they are the linchpin by which we’ll be able to build broadly useful AI models for cell and molecularbiology. Synthesizing a single human protein-coding gene costs several hundred dollars and even a simple PCR machine (used for amplifying DNA) costs between $1,500 and $50,000.
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