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Why genomic healthcare data matters in the development of new therapies 

Drug Discovery World

In April 2003, after its launch in October 1990, the project was completed, generating the first sequence of the human genome. More recently, PacBio begun external beta testing of its Onso Sequencing System, a benchtop short-read DNA sequencing platform utilising PacBio’s sequencing by binding (SBB) technology.

Therapies 246
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Eclectic Genomics: Cat Flu, Dolphin Adaptation to Climate Change, Predicting Cancer, and Diagnosing Rare Disease

PLOS: DNA Science

Genomics applies to all species, revealing evolution in action, because we all use the same genetic code – that is, the correspondence between DNA sequences and the amino acid sequences of proteins. Cats and Bird Flu Comparing DNA sequences is a little like linguistic research that connects languages.

Disease 69
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Where is the drug discovery expertise happening in the UK?

Drug Discovery World

The university aims to identify treatments for life-threatening anti-microbial diseases and metabolic disorders. Our research community of clinicians, clinical trialists, discovery scientists, and statisticians develop pioneering treatments for patients and ground-breaking discoveries in basic science.”

Drugs 189
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China’s National Medical Products Administration approves Benlysta (belimumab) for adult patients with active lupus nephritis

The Pharma Data

GlaxoSmithKline plc (LSE/NYSE: GSK) today announced that China’s National Medical Products Administration (NMPA) has approved Benlysta (belimumab) for the treatment of adult patients with active lupus nephritis (LN) who are receiving standard of care. 8) in combination with standard of care. About lupus.

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New understanding of the TMEJ pathway in cancer

Drug Target Review

Throughout the course of our lives, natural and environmental factors can break DNA. Breaks in both DNA strands are a particularly dangerous threat to genome stability. At a DNA double-strand break (DSB), potentially lost sequence information cannot be recovered from the same DNA molecule.

DNA 58
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Antibody-drug conjugates payloads: then, now and next

Drug Target Review

Antibody-drug conjugates (ADCs) have been a groundbreaking approach to cancer treatment with their ability to deliver cytotoxic drugs directly to diseased cells while sparing healthy tissues. 2 In response, DNA-damaging agents that could target the entire cell cycle received renewed attention as ADC payloads.

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Welcome to Asimov Press

Codon

Recombinant DNA technologies were invented in the 1970s. A first draft of the human genome was completed in 2003. In Switzerland, although evidence for the efficacy of iodized salt was robust, some eminent scientists spoke out against the interventions—advocating for elaborate alternative treatments.