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Scientific workflow for hypothesis testing in drug discovery: Part 1

Drug Target Review

In cases where control or treatment groups show large variability, this could reflect true biological responses to a treatment, and removing such data could reduce the accuracy of the analysis. In 2003, he was selected by EE Times as one of the top 13 most influential people in the semiconductor industry.

RNA 52
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FDA Approves Klisyri (tirbanibulin) for the Treatment of Actinic Keratosis on the Face or Scalp

The Pharma Data

FDA Approves Klisyri (tirbanibulin) for the Treatment of Actinic Keratosis on the Face or Scalp. NASDAQ: ATNX), a global biopharmaceutical company dedicated to the discovery, development, and commercialization of novel therapies for the treatment of cancer and related conditions, today announced that the U.S. BUFFALO, N.Y.,

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New understanding of the TMEJ pathway in cancer

Drug Target Review

She continued: “Now that we know more about this pathway, scientists could, in theory, produce a drug that could disrupt key pieces of the pathway in cancer cells, as opposed to using conventional chemotherapies that destroy healthy cells along with the cancer.” Polymerase theta TMEJ has been the most elusive DNA repair pathway.

DNA 59
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Bridging science and technology: a biotech CEO’s perspective

Drug Target Review

Wilkie’s background as a biochemist and his time at Merck, a leading pharmaceutical company, shaped his early understanding of drug development and business strategy. As someone who describes himself as an “enthusiastic sceptic,” Wilkie is cautious but hopeful about the potential of AI in drug development. “I

Science 52
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Overcoming Healthcare’s Mountain of Mistrust – Part 2: Payers

Perficient: Drug Development

This is a disappointing reversal for payers, as the 2010 results showed a nine-point gain compared to the 2003 figure. Understand the role consumers want you to play In the past, we’ve seen payers provide detailed information on common conditions and treatments covered by their health plans.

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New Drug Miplyffa Approved for Rare Niemann-Pick Disease Type 3

PLOS: DNA Science

FDA approved a treatment for type 3 of the ultra-rare genetic disease September 20. Miplyffa (arimoclomol), an oral drug taken three times a day, is prescribed for patients with Niemann-Pick disease type 3, aka NPD3, two years of age and older. . ” Miplyffa is the first drug developed to treat NPD3 specifically.

Disease 52
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Enlisting Monoclonal Antibodies in the Fight Against COVID-19

NIH Director's Blog: Drug Development

One advantage of this class of therapeutics is that the timelines for their development, testing, and approval are typically shorter than those for drugs made of chemical compounds, called small molecules. So, what exactly led up to this latest scientific achievement?

Virus 52