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Where is the drug discovery expertise happening in the UK?

Drug Discovery World

A company within this ecosystem is STORM Therapeutics, a clinical stage biotechnology company creating novel small molecule therapies that inhibit RNA modifying enzymes (RME) for use in oncology and other diseases. Next, Saleko highligts how Northumberland and the North East of the UK are recognised for pharmaceutical manufacturing prowess.

Drugs 189
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Antibody-drug conjugates payloads: then, now and next

Drug Target Review

Recent efforts are breathing new life into geldanamycin through the construction of a fusion protein made with an anti-HER2 scFv and an HSP90 inhibitor-binding domain (HER2 scFv-HBD), which has resulted in improved anti-cancer efficacy in HER2-positive cancers when loaded with geldanamycin derivatives. 1 , 33–43 (2018). 102 , 1–6 (2016).