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‘Proactive’ vaccine can protect against unknown future coronaviruses

Drug Discovery World

Researchers have developed a new vaccine technology that can provide protection against a broad range of coronaviruses with potential for future disease outbreaks – including ones we don’t know about yet. Building protective vaccines before a pandemic emerges “We don’t have to wait for new coronaviruses to emerge.

Vaccine 130
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Alzheimer’s disease community from our Head of Research and Development, Alfred Sandrock, M.D., Ph.D.

The Pharma Data

Treatment with ADUHELM should be initiated in patients with mild cognitive impairment or mild dementia stage of disease, the population in which treatment was initiated in clinical trials. Continued approval for this indication may be contingent upon verification of clinical benefit in confirmatory trial(s). Biogen Inc.

Disease 52
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AIM ImmunoTech Announces Availability of the ME/CFS Clinical Trial of its Drug Ampligen for Enrollment to COVID-19 ‘Long Haulers’Institutional Review Board Authorizes Public Notification for Potential Enrollment of Subjects

The Pharma Data

Eligible patients enrolled in the trial receive treatment with AIM’s flagship pipeline drug Ampligen. The Ampligen EAP protocol is authorized to enroll up to 100 active trial participants, 20 of whom may be Long Haulers. development pipeline for ME/CFS. All study subjects will receive the same Ampligen treatments. See: PLOS ONE ).

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Enlisting Monoclonal Antibodies in the Fight Against COVID-19

NIH Director's Blog: Drug Development

In a recent paper in the journal Science , researchers used blood drawn from a COVID-19 survivor to identify a pair of previously unknown antibodies that specifically block SARS-CoV-2 from attaching to human cells [2]. They were then able to produce many identical copies of each antibody, referred to as monoclonal antibodies.

Virus 52
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Finding New Ways to Fight Coronavirus … From Studying Bats

NIH Director's Blog: Drug Development

He uses these fundamental insights to guide the design of vaccines and therapeutics, including promising monoclonal antibodies. More importantly for Veesler’s research, bats host a wide range of viruses—more than any other mammal species. But Veesler doesn’t consider himself a visionary by expanding his research to bats.

Virus 52
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Eclectic Genomics: Cat Flu, Dolphin Adaptation to Climate Change, Predicting Cancer, and Diagnosing Rare Disease

PLOS: DNA Science

That information led, thanks to vaccine shelved from the first SARS circa 2003, to the rapid development and deployment of mRNA vaccines against the new infectious disease. I tracked the numbers of sequenced SARS-CoV-2 genomes posted at GISAID every few days during the pandemic, contributed by researchers everywhere.

Disease 92
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European Commission approves Benlysta for adult patients with active lupus nephritis

The Pharma Data

Richard Furie, Chief of the Division of Rheumatology and Professor at the Feinstein Institutes for Medical Research at Northwell Health, and Lead Investigator of the BLISS-LN study commented : “This achievement is derived from decades of research. Immunisation: Do not give live vaccines 30 days before, or concurrently with Benlysta.