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Preliminary Findings from a Phase 2a Trial of Investigational COVID-19 Therapeutic Molnupiravir

The Pharma Data

The companies today reported findings on one secondary objective from the Phase 2a study, showing a reduction in time (days) to negativity of infectious virus isolation in nasopharyngeal swabs from participants with symptomatic SARS-CoV-2 infection, as determined by isolation in Vero cell line culture. About Molnupiravir.

Trials 69
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Roche signs definitive share purchase agreement with long-term partner TIB.

The Pharma Data

The two companies have collaborated for more than 20 years to rapidly address critical healthcare needs including biological threats, such as SARS, anthrax, avian influenza virus H5N1, MERS, the novel influenza virus H1N1 swine, Ebola virus, Zika virus and most recently, SARS-CoV-2 virus and its variants.

Virus 52
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One coronavirus vaccine may protect against other coronaviruse

The Pharma Data

His knowledge about how the HIV virus mutates led him to question cross-reactivity within coronavirus vaccines. ” Years of HIV research led the team to this discovery. Prior to the COVID-19 pandemic, Penaloza-MacMaster had studied HIV vaccines for a decade.

Vaccine 40
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Targovax demonstrates encouraging survival data for ONCOS-102 in mesothelioma

The Pharma Data

1 Vogelzang 2003, Ceresoli 2006, Zalcman 2015, Tsao 2019, Scagliotti 2019, Baas 2020 SITC 2020 poster. An 18-month analysis shows that median Overall Survival (mOS) will be at least 18.2 months for first-line patients receiving ONCOS-102 plus chemotherapy, compared to mOS of 14.2 OSLO, Norway , Nov. References.

Trials 40
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Cave Coronavirus in Wuhan Lab Seeded COVID – The Truth Has Always Been Out There, in the Genetics

PLOS: DNA Science

The virus SARS-CoV-2 emerged in Wuhan, home of a premiere research institute that focuses on viruses. An altered virus could have escaped. Evidence that the virus emerged, or escaped, from the wildlife trade is lacking. Her points: 1. Coincidence? I’ve never thought so. RaTG13 shares about 96.1%

Virus 52
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Blocked Transmission

Codon

It was March 2003, and an unfortunate 33-year-old, known only as patient YY, was suffering from intense diarrhea. Patient YY’s neighbors quickly started to become infected, passing on the virus in turn. Tom Ough writes about how UVC light, metals, and surface coatings can help fend off pathogens for Issue 01. Always free.

Virus 73
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AIM ImmunoTech Announces Availability of the ME/CFS Clinical Trial of its Drug Ampligen for Enrollment to COVID-19 ‘Long Haulers’Institutional Review Board Authorizes Public Notification for Potential Enrollment of Subjects

The Pharma Data

In addition, many survivors of the first SARS-CoV-1 epidemic in 2003 continued to report classic chronic fatigue-like symptoms after recovering from the acute illness. In fact, approximately 27% of survivors in a JAMA Internal Medicine study met the U.S. Centers for Disease Control and Prevention’s criteria for chronic fatigue syndrome.