Elrig

MARCH 25, 2025

Prof Rory Johnson, Associate Professor, University College Dublin, and Dr Shalini Andersson, Vice President Nucleic Acid Therapeutics, AstraZeneca will lead this years event focussed on drugging the undruggable.

RNA 59

RNA Bioinformatics Science Pharmacokinetics 59

Practical Cheminformatics

JANUARY 8, 2024

Picking up where we left off in Part I , this post covers several other ML in drug discovery topics that interested me in 2023. Most of the LLM activity in the drug discovery space in 2023 was reported as preprints from academic groups. Most of the drug discovery examples were underwhelming. Here’s the structure of Part II.

Drugs 136

Drugs Small Molecule Bioinformatics Packaging 136

Drug Target Review

DECEMBER 28, 2023

Recent advances in bioinformatics show clonal neoantigens are the best targets for immunotherapy, as I will elucidate below. Using powerful bioinformatics technology developed and validated with sequence data from the TRACERx study, researchers are able to identify clonal neoantigens from a patient’s unique tumour profile.

Bioinformatics 105

Bioinformatics Immune Response DNA Vaccine 105

Codon

AUGUST 10, 2023

Drug Discovery Today: Disease Models (2008). Link Production of the antimalarial drug precursor artemisinic acid in engineered yeast , by Ro D-K. PNAS (2004). Link Artificial Gene Regulatory Networks—A Review , by Cussat-Blanc S. Artificial Life (2018). Link Mathematical modeling and synthetic biology , by Chandran D.

DNA 98

DNA Cell Biology Molecular Biology Engineering 98

Codon

AUGUST 10, 2023

Drug Discovery Today: Disease Models (2008). Link Production of the antimalarial drug precursor artemisinic acid in engineered yeast , by Ro D-K. PNAS (2004). Link Artificial Gene Regulatory Networks—A Review , by Cussat-Blanc S. Artificial Life (2018). Link Mathematical modeling and synthetic biology , by Chandran D.

DNA 52

DNA Cell Biology Engineering Molecular Biology 52