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Cholesterol Med, Fenofibrate, Might Slow Vision Loss in People With Diabetes

Drugs.com

TUESDAY, June 25, 2024 -- A well-established cholesterol-lowering drug appears to significantly slow the progression of a diabetes-related eye disease, a new trial shows. Fenofibrate (Tricor) has been approved since 2004 as a means of lowering.

Trials 279
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Cholesterol Med Might Slow Vision Loss in People With Diabetes

Drugs.com

TUESDAY, June 25, 2024 -- A well-established cholesterol-lowering drug appears to significantly slow the progression of a diabetes-related eye disease, a new trial shows.Fenofibrate (Tricor) has been approved since 2004 as a means of lowering.

Trials 246
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The genetic modifier approach: identifying the right target for rare diseases

Drug Target Review

Most rare diseases are caused by a single gene defect, but severity can vary considerably among patients. Modifier genes can help explain that variability and can alter or even prevent disease onset and progression, making them appealing therapeutic targets. However, the identification of these genes is challenging.

Disease 111
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Therapeutic Oligos 2025 Keynote Speakers Announced

Elrig

It will also cover recent advancements in broadening their application, including innovative approaches to ensure their safety and efficacy, the use of targeted delivery to reach disease-relevant tissues as well as success stories in bringing therapeutic oligonucleotides to the clinic.

RNA 59
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Brain Disease Model of Addiction

Common Sense for Drug Policy Blog

Brain Disease Model of Addiction "In 1997, Alan Leshner, the Director of the US National Institute on Drug Abuse (NIDA), proclaimed that addiction was a chronic, relapsing, brain disease ( Leshner, 1997 ). This has been called the brain disease model of addiction (BDMA). Drug Alcohol Depend. 2023;253:111033. 2023.111033

Disease 52
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Q&A: Single-cell and spatial proteomics reveal proteins’ nuanced roles in health and disease

Broad Institute

In doing that, we lost information about the uniqueness of each cell, and we had limited information about the spatial heterogeneity of tissues that plays a decisive role in disease. Single-cell genomics has really transformed our understanding of how cells work in health and disease.

Disease 85
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Stem cell therapy to slow progression of multiple sclerosis (MS)

Drug Target Review

The first instance of aHSCT in this cohort dates to 2004, and the average age of these patients at the time of treatment was 31, with a majority of them being women, accounting for 64 percent of the group. Around three years following their aHSCT, 20 patients (11 percent) were administered disease-modifying drugs.

Therapies 116