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Mediating BRAF-mutant melanoma resistance

Drug Target Review

Our data demonstrate that the CoREST complex is a critical mediator of the distinct melanoma phenotypes, working through the regulation of both the phenotype-defining genes MITF and AXL as well as the master regulators of epithelial-to-mesenchymal transitions (EMT) and phenotype switching in melanoma and other cancers, SNAIL/SLUG/ZEB1/ZEB2.

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Scaling Phage Therapy

Codon

By 2004, over a dozen companies were working on developing phage products and therapies, in locations ranging from Baltimore to Bangalore, where ten years previously, there had been none. It took two years to produce the phage cocktail to standards that regulators were happy with.

Therapies 115
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Measure Cell Metabolism with Microplate Readers | BMG LABTECH

BMG Labtech

In fact, metabolism should not be considered as a self-regulating entity that is independent of other biological pathways. Alberts B, How Cells Obtain Energy from Food, Molecular Biology of the Cell (4th ed.). Alberts B, 2002, Energy Conversion: Mitochondria and Chloroplasts, Molecular Biology of the Cell (4th ed.).

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The Codon Guide to Synthetic Biology

Codon

Link Gene Expression & Regulation →Genetic regulatory mechanisms in the synthesis of proteins , by Jacob F. & Journal of Molecular Biology (1961). Gene Expression and Regulation. Nature Reviews Molecular Cell Biology (2008). Link Molecular Cloning Techniques , by AddGene. & Xie X.S.

DNA 90
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The Codon Guide to Synthetic Biology

Codon

Link Gene Expression & Regulation →Genetic regulatory mechanisms in the synthesis of proteins , by Jacob F. & Journal of Molecular Biology (1961). Gene Expression and Regulation. Nature Reviews Molecular Cell Biology (2008). Link Molecular Cloning Techniques , by AddGene. & Xie X.S.

DNA 52