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Our data demonstrate that the CoREST complex is a critical mediator of the distinct melanoma phenotypes, working through the regulation of both the phenotype-defining genes MITF and AXL as well as the master regulators of epithelial-to-mesenchymal transitions (EMT) and phenotype switching in melanoma and other cancers, SNAIL/SLUG/ZEB1/ZEB2.
By 2004, over a dozen companies were working on developing phage products and therapies, in locations ranging from Baltimore to Bangalore, where ten years previously, there had been none. It took two years to produce the phage cocktail to standards that regulators were happy with.
In fact, metabolism should not be considered as a self-regulating entity that is independent of other biological pathways. Alberts B, How Cells Obtain Energy from Food, MolecularBiology of the Cell (4th ed.). Alberts B, 2002, Energy Conversion: Mitochondria and Chloroplasts, MolecularBiology of the Cell (4th ed.).
Protein nitration is one example that takes place on tyrosine residues which can have important consequences for the regulation of biological processes. Protein nitration assays are widely used in many research areas including but not limited to biochemistry , biotechnology , cell biology , microbiology , and molecularbiology.
Link Gene Expression & Regulation →Genetic regulatory mechanisms in the synthesis of proteins , by Jacob F. & Journal of MolecularBiology (1961). Gene Expression and Regulation. Nature Reviews Molecular Cell Biology (2008). Link Molecular Cloning Techniques , by AddGene. & Xie X.S.
Link Gene Expression & Regulation →Genetic regulatory mechanisms in the synthesis of proteins , by Jacob F. & Journal of MolecularBiology (1961). Gene Expression and Regulation. Nature Reviews Molecular Cell Biology (2008). Link Molecular Cloning Techniques , by AddGene. & Xie X.S.
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