Elrig

MARCH 25, 2025

Earlier in her career, she held several leadership roles within AstraZeneca, including Senior Director for Drug Metabolism & Pharmacokinetics and Director for Lead Optimisation & Enabling Technologies within medicinal chemistry.

RNA 59

RNA Bioinformatics Science Pharmacokinetics 59

Practical Cheminformatics

JANUARY 8, 2024

While large pharmaceutical companies have data on thousands or even millions of compounds, this data is rarely shared due to intellectual property concerns. A 2004 paper by Vigers and Rizzi proposed a similar strategy for docking studies. For classification models, the participants reported a median 2.5-7.5% What’s old is new again.

Drugs 136

Drugs Small Molecule Bioinformatics Packaging 136

New Drug Approvals

JANUARY 9, 2024

1004-1014, 2004). For drug development, it is typically advantageous to employ individual stereoisomers as they exhibit marked differences in pharmacodynamic, pharmacokinetic, and toxicological properties. 2006 Mar 1; 20(5):601-12, 2006), in contrast with CDK9, which phosphorylates both Ser-2 and Ser-5 of the CTD heptad (Pinhero et al.,

Production 62

Production DNA RNA Regulations 62

Agency IQ

FEBRUARY 12, 2024

Another guidance will focus on pharmacokinetics in pregnancy, likely replacing a 2004 guidance document that the FDA never finalized, while a guidance the creation of a “REMS Logic Model” framework is meant to “link program design with assessment” – something called for in the most recent PDUFA VII commitment letter.

Biosimilars 40

Biosimilars Science Clinical Pharmacology FDA 40

The Pharma Data

JULY 23, 2021

The antibody combination was granted a Special Approval Pathway under article 14-3 of the Pharmaceuticals and Medical Devices Act. In October 2020, Roche announced a partnership with Atea Pharmaceuticals to jointly develop the investigational compound AT-527.

Treatment 52

Treatment Virus Clinical Trials Pharmaceuticals 52

New Drug Approvals

APRIL 14, 2025

PATENT Arena Pharmaceuticals, Inc.WO2023172685 Arena Pharmaceuticals, Inc., 1] [3] It is being developed by Longboard Pharmaceuticals. [1] 5] [6] [7] References ^ Jump up to: a b c d e f “Bexicaserin – Longboard Pharmaceuticals” AdisInsight. Menendez de la Prida L, Gal B (June 2004). 2017.00060.

Clinical Trials 62

Clinical Trials Pharmaceuticals Pharmacokinetics Treatment 62

New Drug Approvals

APRIL 5, 2025

15] In February 2004, orphan designation (EU/3/04/186) was granted by the European Commission to medac Gesellschaft fuer klinische Spezialprparate mbH, Germany, for treosulfan for the conditioning treatment prior to haematopoietic progenitor cell transplantation. [16] 155 and Organic.Syntheses, (2004), Coll.Vol.10, 21 December 2022.

FDA 62

FDA FDA Approval Production Treatment 62