Drug Target Review

NOVEMBER 17, 2023

She obtained her PhD from the University of Wollongong in 2015 and gained extensive research experience as a postdoctoral fellow at Swinburne University of Technology, CSIRO, and Monash University, in the fields of immunology and tissue engineering. Alan founded the Monash Immunology and Stem Cell Laboratories at Monash University (2004-7).

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PPD

FEBRUARY 19, 2024

The European Union Clinical Trial Regulation (EU CTR) brings the biggest change in the regulatory landscape since the implementation of the EU Clinical Trials Directive in 2004, requiring vast changes in the way organizations are structured and conduct their day-to-day activities.

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Drug Target Review

SEPTEMBER 21, 2023

Introduction I clearly remember an incident as a researcher, which kept happening, from my undergraduate research up till now. Summary of research The undergraduate study concentrated on the potential adulticidal effects of oral analgesics (acetaminophen, aspirin, and ibuprofen) on Onchocerca volvulus. doi: 10.1002/14651858.CD011146.pub2.

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Drug Target Review

DECEMBER 28, 2023

Using powerful bioinformatics technology developed and validated with sequence data from the TRACERx study, researchers are able to identify clonal neoantigens from a patient’s unique tumour profile. Researchers believe supplementing bioinformatics with artificial intelligence trained on real-world data will provide the answer.

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Broad Institute

APRIL 26, 2024

Celebrating Broad’s 20th Anniversary By Maria Nemchuk April 26, 2024 Celebrating Broad’s 20th Anniversary In 2004, the Broad Institute was founded with an ambitious goal: to leverage the newly sequenced human genome and fulfill the promise of genomic medicine.

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Drug Target Review

JULY 4, 2023

For instance, we can compare the data from the 2021 DESTINY gastric cancer trial using the ADC Trastuzumab Deruxtecan with data from a gastric cancer trial in 2004 using the small molecule Irinotecan. In both cases, the active ingredients are camptothecin-derived topoisomerase 1 inhibitors with similar proposed modes of action.

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The Pharma Data

DECEMBER 22, 2020

from the University of Mississippi in Jackson, and colleagues explored the association between goal-striving stress (GSS) and RKFD among 2,630 African Americans using data from the Jackson Heart Study (2000 to 2004 and 2009 to 2013). The researchers found that the incidence of RKFD in this sample was 7.34 Loretta Cain-Shields, Ph.D.,

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Drug Target Review

JUNE 19, 2024

Because this programme is still in early research, we are not at a point we can say we definitely know what it is going to work best in setting X or setting Y. From 2002 until 2004, Mr Culley was Director of Business Development and Marketing for Immusol, Inc. Mr Culley served on the Board of Orphagen Pharmaceuticals, Inc.

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Therapies Small Molecule Pharmaceutical Companies Molecular Biology 84

The Pharma Data

NOVEMBER 16, 2020

Siu Long Lee, from University College London, and colleagues evaluated the association between loneliness and depressive symptoms using data from adults aged 50 years and older in England participating in seven waves of the English Longitudinal Study of Aging (2004 to 2017; 4,211 participants).

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PLOS: DNA Science

MARCH 28, 2024

It “could have been easily repurposed for DMD,” said Pier Lorenzo Puri at Sanford Burnham Prebys Medical Discovery Institute in San Diego, who has been working on the drug development since 2004. Research also took place in two facilities in Italy, with sponsorship from Italfarmaco S.p.A.

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Sygnature Discovery

JULY 31, 2023

Leading integrated drug discovery partner, Sygnature Discovery (“Sygnature”) has announced its acquisition of one of North America’s largest discovery Contract Research Organisations, Canada-based NuChem Sciences. Its staff of over 1,000, which includes 900 scientists, partners with global pharma, biotech and NFP organisations.

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Computational Chemistry Science Clinical Trials Pharmaceutical Companies 52

Broad Institute

AUGUST 2, 2023

The design of STAR leverages unique characteristics of the 2004 tsunami to provide plausibly-causal estimates of the ramifications of disasters and traumatic exposures. The 2004 tsunami was a massive tragedy, with waves of over 30m impacting the coastline. Helsinki Center of Economic Research, Helsinki 2013).

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Medical Schools Disease Science International 52

The Pharma Data

MARCH 4, 2021

In addition to his duties, Christian Brandts is pursuing his research activities focused mainly on translational cancer research and personalized oncology. In 2004, she was appointed Global Chief Procurement Officer for all global purchases at L’Oréal, and in 2012, General Manager for Travel Retail department.

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The Pharma Data

DECEMBER 10, 2020

A new study from researchers in Sweden and the United Kingdom found that owning a dog with diabetes was tied to a 38% increased risk of type 2 diabetes for the dog owner. 1, 2004 and Dec. More than 400 million people worldwide now have type 2 diabetes and the number is likely to grow, the researchers said. THURSDAY, Dec.

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Hospitals Disease Research Drugs 52

Sygnature Discovery

AUGUST 20, 2024

World-leading contract research organization Sygnature Discovery has announced a major new addition to its leadership team, with the high-profile appointment of industry veteran Jade Dagher as General Manager, Canada. Additional sites are located in Alderley Park, Macclesfield, and Glasgow (UK), as well as Montreal and Quebec City (Canada).

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The Pharma Data

NOVEMBER 6, 2020

She was employed by the university as a researcher from 1987 until 1988. Amy Dryman, DSc is a coauthor of research papers in psychiatric epidemiology that have been published and referenced in professional journals. Dr. Dryman continued her employment with the company as a manager from 2001 until 2004.

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Sygnature Discovery

SEPTEMBER 14, 2023

Sygnature Discovery is delighted to announce that its customer, River BioMedics , has raised an additional €2M in seed funding to continue its life-saving cardiovascular drug research. Since 2004, Sygnature Discovery has delivered over 40 novel pre-clinical and 22 clinical compounds, with its scientists named on over 170 patents.

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The Pharma Data

SEPTEMBER 15, 2020

During her medical practice, Seredina worked in clinical research as an investigator. The results of her research were published in a number of articles highlighting her knowledge of the critical challenges of clinical sites and of the importance of being patient-centric.

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Codon

FEBRUARY 13, 2024

Goodsell, RCSB Protein Data Bank and Scripps Research. By 2004, over a dozen companies were working on developing phage products and therapies, in locations ranging from Baltimore to Bangalore, where ten years previously, there had been none. Tom Ireland writes about the companies and technologies that are reimagining phage therapy.

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Pharmaceutical Development Group

AUGUST 9, 2021

Biotechnology and genomics businesses were projected to perform around one-fifth of all pharmaceutical research and development in 2004. (R&D). Many pharmaceutical goods would not have been possible without the use of biotechnologies over time.

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PLOS: DNA Science

AUGUST 17, 2023

That was the case for the approximately 250,000 bodies that the Indian Ocean tsunami in 2004 scattered about, which rapidly decayed in the hot, wet climate. So the researchers turned to the older way to match people for organ transplants, variability of the six human leukocyte antigen (HLA) genes.

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DNA Disease Science Research 98

Elrig

SEPTEMBER 13, 2024

Dr Rob Howes, Senior Director, Charles River Laboratories will work to represent the contract research organisations as well as to start ELRIGs sustainability plan. ELRIG UK, the leading organiser of scientific conferences for the life science community, announces Board changes to enable continuing growth.

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Science Laboratories Government Research 52

Broad Institute

SEPTEMBER 5, 2024

This progress is in part driven by optimized methods and more powerful tools developed by researchers such as Claudia Ctortecka, a postdoctoral associate in the Proteomics Platform headed by Carr, and colleagues in the Platform.

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Sygnature Discovery

NOVEMBER 2, 2023

About Sygnature Discovery Sygnature Discovery is a world-leading integrated drug discovery Contract Research Organisation based in the UK and Canada with its headquarters in Nottingham and additional sites in Alderley Park, Macclesfield, Glasgow, Montreal and Quebec City.

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Science Disease Drugs Marketing 52

The Pharma Data

NOVEMBER 18, 2020

The foundation of WHO’s recommendation is the development, by countries, of a 5-year national action plan on HIV drug resistance , which is aligned with the 5 key pillars of the Global action plan on HIV drug resistance : prevention and response, monitoring and surveillance, research and innovation, laboratory capacity, and.

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Laboratories Therapies Virus Government 52

Drug Target Review

FEBRUARY 26, 2024

Her research focus is on epigenetic regulation of melanoma and other cancers as well as wound healing, ageing biology and the development of novel epigenetic therapies targeting cancers and skin diseases and she is the owner of 15 issued and pending patents relevant to her research. Dr Alani received her M.D.

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Sygnature Discovery

SEPTEMBER 25, 2023

About Sygnature Discovery Sygnature Discovery is a world-leading integrated drug discovery Contract Research Organisation based in the UK and Canada with its headquarters in Nottingham and additional sites in Alderley Park, Macclesfield, Glasgow, Montreal and Quebec City.

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NIH Director's Blog: Drug Development

OCTOBER 27, 2020

With the aim of developing such protein-targeted antiviral drugs, a large, international team of researchers, funded in part by the NIH, has precisely and exhaustively mapped all of the interactions that take place between SARS-CoV-2 proteins and the human proteins found within infected host cells.

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Drug Development Drugs Virus Science 52

Sygnature Discovery

OCTOBER 10, 2023

Human iPSC-derived cells are stem cells derived from patient donors that are a powerful tool in biomedical research due to their ability to differentiate into various cell types found in the human body. The collaboration aims to explore the incorporation of human iPSC-derived microglia into high-content imaging in vitro screening workflows.

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Drug Target Review

SEPTEMBER 20, 2023

Author bio: Matthew Habgood Principal Computational Chemist, Cresset Matthew graduated from Imperial College London in 2004 with an MSci in Chemistry and was co-awardee of the Neil Arnott prize for best chemistry graduate at the University of London. Previous roles include CEO of Amedis and VP, Europe at CambridgeSoft.

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Drug Target Review

FEBRUARY 5, 2024

Dr Ashley Seifert, an associate professor in the Department of Biology at the UK College of Arts and Sciences, and his research group have pioneered the use of spiny mice and other animal models to understand how complex tissue can regenerate, bridging regenerative biology and medicine. 22 June 2004 [2024 January 26].

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Laboratories Immune Response RNA Regulations 59

Drug Target Review

JUNE 21, 2023

The modest sample sizes which are typical in rare disease research make it inherenttly challenging to obtain sufficient power to confidently associate gene variants to phenotypes. 14 In particular in baker’s yeast, researchers could systematically identify gene-gene interactions, including genetic suppressors.

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National Institute on Drug Abuse: Nora's Blog

MARCH 6, 2025

Thus, the NIH and FDA have recently called for consideration of meaningful study endpoints in addition to abstinence in research on new smoking-cessation products 6 ; though abstinence is still required as the main outcome for medication approval. 2004 Jan;65(1):105-14. October 2020. Retrieved March 6, 2025, [link] U.S. 2015;2:11321.

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Sygnature Discovery

MARCH 24, 2022

When DMPK scientist Lynette Ongeri joined Sygnature this month, she unknowingly helped us reach a landmark we couldn’t be prouder of… Sygnature Discovery – or Sygnature Chemical Services Ltd, as it was known then – opened its doors in 2004 with five colleagues.

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Computational Chemistry International Science Pharmaceuticals 52

The Pharma Data

APRIL 18, 2022

In August 2004, the Food Allergen Labeling and Consumer Protection Act (FALCPA) was signed into law. On April 23, 2021, the Food Allergy Safety, Treatment, Education, and Research (FASTER) Act was signed into law, declaring sesame as the 9th major food allergen recognized by the U.S., effective Jan. 1, 2023.

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Perficient: Drug Development

MARCH 5, 2024

These should not be topics geared toward an academic, researcher or provider audience. However, if your experts are taking part in research whose results you can gear toward a layperson audience, that can be a great way to showcase the expertise your organization brings to the communities you serve.

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Drug Target Review

JANUARY 9, 2024

Presently, it is unknown how anthrobots encourage the growth of neurons, although the researchers confirmed that neurons grew under the area covered by a cluster of anthrobots, termed a “superbot.” 2004 July [2023 December 18]; 45(4):354-60. Anthrobots Anthrobots begin as a single cell from an adult donor. Immunosuppressants.

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