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How Targeted Cancer Drugs Disrupt the Cell Cycle

PLOS: DNA Science

A “DNA damage checkpoint” rests the cell cycle while special proteins repair damaged DNA. Cancer cells make too much survivin, with levels increasing as the disease spreads and becomes more aggressive. It delayed disease progression and more than doubled survival time, adding 17 months. Blood cancer.

Drugs 52
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The Codon Guide to Synthetic Biology

Codon

Nature (2005). Drug Discovery Today: Disease Models (2008). Technologies DNA Sequencing →DNA sequencing at 40: past, present and future , by Shendure J. Link DNA Cost and Productivity Data, aka "Carlson Curves" , by Carlson R. Link Next-Generation DNA Sequencing Methods , by Mardis E.R. Nature (2017).

DNA 91
article thumbnail

The Codon Guide to Synthetic Biology

Codon

Nature (2005). Drug Discovery Today: Disease Models (2008). Technologies DNA Sequencing →DNA sequencing at 40: past, present and future , by Shendure J. Link DNA Cost and Productivity Data, aka "Carlson Curves" , by Carlson R. Link Next-Generation DNA Sequencing Methods , by Mardis E.R. Nature (2017).

DNA 52