How Targeted Cancer Drugs Disrupt the Cell Cycle
PLOS: DNA Science
JUNE 22, 2023
A “DNA damage checkpoint” rests the cell cycle while special proteins repair damaged DNA. The candidate drug, vorasidenib, is a small molecule that inhibits survivin. I had the privilege to meet one of the first people to receive Gleevec, which I wrote about for Bioethics Today in 2006. Blood cancer.
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