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How nucleolar stress accelerates aging in mice

Drug Target Review

How has nucleolar stress (NS) been linked to age-related diseases, and what approach did researchers use to investigate its toxicity? The nucleolus (and nucleolar stress) had been previously linked to aging and age-related diseases such as cancer or degeneration.

RNA 62
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Discovering an Antimalarial Drug in Mao’s China

Codon

“Cumulatively the deadliest of the human infectious diseases,” malaria has been documented throughout recorded history. In this light, scouring old Chinese remedies for new treatments for a disease specifically troublesome during war was entirely intuitive for Chinese biomedical scientists like Tu Youyou in the mid-20th century.

Drugs 141
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Precision Medicine in the Genomic Era

DrugBank

Out of the millions of genetic variants present in human populations, GWAS are designed to uncover those associated with specific traits or diseases. Their use, as well as their integration into other types of data, has enabled the development of more precise therapies.

Disease 88
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The Codon Guide to Synthetic Biology

Codon

” Foundations Basics of Synthetic Biology →Foundations for engineering biology , by Endy D. Nature (2005). Link →A brief history of synthetic biology , by Cameron D.E. Link Synthetic biology: applications come of age , by Khalil A.S. & Nature Reviews Molecular Cell Biology (2009).

DNA 98
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The Codon Guide to Synthetic Biology

Codon

” Foundations Basics of Synthetic Biology →Foundations for engineering biology , by Endy D. Nature (2005). Link →A brief history of synthetic biology , by Cameron D.E. Link Synthetic biology: applications come of age , by Khalil A.S. & Nature Reviews Molecular Cell Biology (2009).

DNA 52