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For his postdoctoral stay he joined the group of André Nussenzweig, where he started to work on DNA repair, particularly focusing on the role of histone H2AX. In 2005, he joined CNIO to lead the Genomic Instability Group where he has been ever since.
In contrast, non-coding mutations have effects on gene expression, transcript stability, and the physical state of the DNA itself (e.g., Conclusion Since the first GWAS was published in 2005, there have been more than 50,000 significant variant-trait associations identified. by altering its accessibility to transcriptional machinery).
” Foundations Basics of Synthetic Biology →Foundations for engineering biology , by Endy D. Nature (2005). Link →A brief history of synthetic biology , by Cameron D.E. Link Synthetic biology: applications come of age , by Khalil A.S. & Nature Reviews Molecular CellBiology (2009).
” Foundations Basics of Synthetic Biology →Foundations for engineering biology , by Endy D. Nature (2005). Link →A brief history of synthetic biology , by Cameron D.E. Link Synthetic biology: applications come of age , by Khalil A.S. & Nature Reviews Molecular CellBiology (2009).
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