Drug Target Review

FEBRUARY 28, 2024

gammadelta T cells link innate and adaptive immune responses. Chem Immunol Allergy 86:151-183 (2005). Normality sensing licenses local T cells for innate-like tissue surveillance. Regulation of cutaneous malignancy by gammadelta T cells. References Fichtner A, Ravens S, Prinz I. Cells 9(40):800 (2020).

Therapies 103

Therapies Engineering Molecular Biology Immune Response 103

The Pharma Data

NOVEMBER 9, 2020

Specifically, tezepelumab targets and blocks TSLP, a key epithelial cytokine that sits at the top of multiple inflammatory cascades and initiates an overreactive immune response to allergic, eosinophilic and other types of airway inflammation associated with severe asthma. 2005; 172; 149–60. J Intern Med 2012;272:121–32.

Trials 52

Trials Production Clinical Trials Government 52

The Pharma Data

DECEMBER 21, 2020

Specifically, tezepelumab targets and blocks TSLP, a key epithelial cytokine that sits at the top of multiple inflammatory cascades and initiates an overreactive immune response to allergic, eosinophilic and other types of airway inflammation associated with severe asthma. 2005; 172: 149-160. 2019;12(5):539-549.

Trials 40

Trials Production Clinical Trials Government 40