New Drug Approvals

SEPTEMBER 8, 2024

5 On August 14, 2024, seladelpar was granted accelerated approval by the FDA for the treatment of primary biliary cholangitis, 6 which is a condition associated with aberrant bile acid metabolism. July 2024). “Seladelpar treatment reduces IL-31 and pruritus in patients with primary biliary cholangitis” Hepatology.

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Drug Target Review

MAY 23, 2023

Therapies developed in recent decades have transformed the treatment of IBD, making hospitalisation and surgery less common. However, many patients respond poorly to corticosteroid treatment, or their immune system responds unfavourably to biological therapies, such as the development of autoimmune diseases. 7 (Suppl 2), S4 (2005).

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Drug Target Review

FEBRUARY 28, 2024

Over the past 25 years, T-cell therapies have gained significant ground in the treatment of cancer. Chem Immunol Allergy 86:151-183 (2005). A combined treatment regimen of MGMT-modified γδ T cells and temozolomide chemotherapy is effective against primary high grade gliomas. Human γδ TCR repertoires in health and disease.

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The Pharma Data

JUNE 25, 2021

protofibril antibody for the treatment of Alzheimer’s disease (AD). 1 The proof-of-concept Study 201 explored the impact of treatment with lecanemab on reducing brain amyloid beta (A?) Food and Drug Administration (FDA) has granted Breakthrough Therapy designation for lecanemab (BAN2401), an investigational anti-amyloid beta (A?)

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The Pharma Data

APRIL 27, 2021

Roche announces five new intended uses for key cardiac biomarkers to help identify cardiovascular risk, better diagnose patients and support early treatment. Early diagnosis and treatment can contribute to saving or improving people’s lives and could help healthcare systems save money.

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The Pharma Data

NOVEMBER 23, 2020

Legend was launched to expand GenScript’s capabilities of developing a broad range of immunotherapy treatments. Food and Drug Administration last year and appears to be on track for a potential regulatory review as a treatment for multiple myeloma next year. Cilta-cel snagged Breakthrough Therapy Designation from the U.S.

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Drug Target Review

FEBRUARY 7, 2024

The gene expression ‘transcriptome’ from the cell type we studied has a p-value that is better than this by a factor of 500,000x. How do the findings of the research reveal the potential treatments options for COVID-19, particularly in terms of managing excessive inflammation and targeting specific enzymes?

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The Pharma Data

FEBRUARY 22, 2022

He is co-founder and non-executive board member of the Hartwig Medical Foundation (large scale DNA analyses) and is a board member of the Center for Personalized Cancer Treatment and leads several innovative precision oncology clinical trials. He has founded and leads several innovative precision medicine initiatives in oncology.

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The Pharma Data

MARCH 11, 2021

Actemra/RoActemra is not approved for the treatment of COVID-19 pneumonia. The antiviral medication Veklury was invented and developed by Gilead Sciences and is approved or authorized for temporary use for the treatment of COVID-19 in approximately 50 countries worldwide. Ltd and has been approved in Japan since April 2005.

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The Pharma Data

MARCH 5, 2021

Food and Drug Administration (FDA) approved Actemra ® /RoActemra ® (tocilizumab) subcutaneous injection for slowing the rate of decline in pulmonary function in adult patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD), a debilitating condition with limited treatment options. 1-3 SSc affects about 2.5

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The Pharma Data

JANUARY 6, 2021

The ongoing coronavirus pandemic and the lack of treatment options for severe cases has been devastating for patients, their families and medical communities around the world,” commented Erik van den Berg , Chief Executive Officer at AM-Pharma. 7, 2021 10:00 UTC. UTRECHT, The Netherlands–( BUSINESS WIRE )– AM-Pharma B.V. ,

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The Pharma Data

DECEMBER 2, 2020

Philippe Archinard has led the company since 2005 and will remain a member of the Board of Transgene. Under his leadership, the Company has demonstrated the potential of virus-based immunotherapies and developed world class innovative therapies that could be game-changers in the field of cancer treatment.

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DrugBank

JUNE 27, 2023

The general notion is that patients should be viewed individually, rather than strictly as members of some larger general population, and that their specific genetic background, environment, and lifestyle choices should be considered throughout drug development to the point of treatment and continuing patient care.

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The Pharma Data

SEPTEMBER 2, 2021

Interim analysis of patient engagement and adherence assessment indicates ability of Enerzair Breezhaler optional digital companion (sensor and app) in supporting patient engagement and treatment adherence 6. Woehrle et al. Details: Oral Presentation, 7 September, 14:45-16:15 CEST. About Enerzair ® Breezhaler ® in the European Union (EU).

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The Pharma Data

DECEMBER 14, 2020

DetermaRx is a treatment stratification test that identifies stage I-IIA non-squamous NSCLC patients at high-risk of recurrence despite ostensibly curative surgery, who may benefit from the addition of chemotherapy. “We Management of such patients depends on prognostic staging to identify the individuals most likely to have occult disease.

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Broad Institute

JANUARY 30, 2024

In others, an infection can cause the immune system to spin out of control, leading to sepsis — organ dysfunction that lacks effective treatments and is often fatal. In 2005, Bhattacharyya completed PhD studies at the University of California, San Francisco, in biochemistry and molecular biology, followed by two years of medical training.

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The Pharma Data

MAY 5, 2022

Launched in 2005 to give every child an equal chance of survival, ‘My Child Matters’ provides financial support and expertise so that all children can access diagnosis and treatment. Sanofi is listed on EURONEXT: SAN and NASDAQ: SNY.

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The Pharma Data

JULY 29, 2021

Eisai and Biogen Present Preliminary Assessment of the Clinical Effects of Lecanemab Following 18 Months of Treatment in the Open-Label Extension of the Phase 2 Proof of Concept Study at 2021 Alzheimer’s Association International Conference (AAIC) . 42/40 ratio, brain amyloid by PET and treatment Low values of plasma A?42/40

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The Pharma Data

JANUARY 18, 2021

Fox Foundation continues to fund our cutting-edge science in their mission to transform the way new Parkinson’s disease treatments are developed and tested,” says Dr. Charlotte D’Hulst, CEO & Co-Founder of Yesse Technologies, Inc. “We are thrilled that The Michael J. View original content: [link]. Source link.

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PLOS: DNA Science

APRIL 13, 2023

received treatment, according to the National Institute on Drug Abuse (NIDA). So scrutinizing genomes for genes that control drug dependency could inspire treatments. The first SNP map was published in 2001 and the first GWAS in 2005. Drug addiction is prevalent and deadly. That’s the goal of the new report.

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The Pharma Data

DECEMBER 18, 2020

They are routinely used in hospitals to help providers make treatment decisions. Back in 2005, a small study found that the devices tended to overestimate oxygen levels in dark-skinned patients. And during the COVID-19 pandemic, pulse oximeters have increasingly made their way into the hands of lay people.

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FDA Law Blog: Biosimilars

MAY 23, 2023

Part 117, and the Food Allergy Safety, Treatment, Education and Research Act (2021). the product label declares “tree nut” or “fish” but fails to declare the type of tree nut or species of fish in either the ingredient list or in a separate “Contains” statement).

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Common Sense for Drug Policy Blog

JANUARY 1, 2024

Multiplying the lifetime costs of HIV treatment per person ($229,800) 25 by the average number of diagnoses averted annually in both cities yields an estimated annual saving of $243.4 The forecasts estimated an average of 1059 HIV diagnoses in Philadelphia and 189 HIV diagnoses in Baltimore averted annually. million for Philadelphia and $62.4

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The Pharma Data

NOVEMBER 25, 2020

A new website takeironseriously.com has been launched to educate individuals and healthcare professionals on the symptoms of iron deficiency, demonstrate the ease of diagnosis and encourage people to seek treatment to protect their health. Guidelines on the diagnosis and treatment of iron deficiency across indications: a systematic review.

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The Pharma Data

NOVEMBER 26, 2020

“When we get market approval for Sedaconda, we can exclusively launch the treatment inhaled sedation in Europe. The treatment consists of our drug Sedaconda, which is then approved for administration only via our medical device AnaConDa. This information was brought to you by Cision [link].

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The Pharma Data

MARCH 17, 2022

AstraZeneca today launched a global R&D Postdoctoral Challenge to help accelerate ideas to transform the treatment of some of the world’s most complex diseases. Successful proposals will secure fully funded postdoctoral research positions.

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The Pharma Data

NOVEMBER 9, 2020

The Chair of the Review Committee on the functioning of the International Health Regulations (2005) during COVID-19 response , Professor Lothar H. Wieler, President of the Robert Koch Institute, Germany provided an update on the work of the Committee and its preliminary findings. billion financing gap.

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The Pharma Data

OCTOBER 20, 2020

8 months in similar patients with metastatic breast cancer in the third line setting without BriaCell’s treatment; Additional overall survival data will be presented at the 2020 San Antonio Breast Cancer Symposium®, December 9 – 11. Overall Survival of 13. BERKELEY, Calif. and VANCOUVER, British Columbia, Oct.

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The Pharma Data

DECEMBER 14, 2020

About Bay Area Oral Surgery Management Since 2005, Bay Area Oral Surgery Management’s mission has been to provide excellence in surgical oral care. AOFS is led by 25 highly skilled oral surgeons, providing comprehensive oral and maxillofacial services.

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The Pharma Data

NOVEMBER 9, 2020

NAVIGATOR is a Phase 3, randomized, double-blinded, placebo-controlled trial in adults (18–80 years old) and adolescents (12–17 years old) with severe, uncontrolled asthma, who were receiving treatment with medium- or high-dose ICS plus at least one additional controller medication with or without OCS. 2005; 172; 149–60. 7 Wenzel S.

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Agency IQ

APRIL 19, 2024

Treatment for MM may be lifelong, with patient and disease characteristics guiding the course of treatment. Patients frequently receive up to four therapies at once and go through multiple prolonged courses of treatment to keep recurrence and progression at bay.

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Agency IQ

FEBRUARY 2, 2024

In 2005, the guidance was updated to include non-cytotoxic drugs were gaining in importance. Predictive biomarkers enable the identification and selection of patients who are more likely to benefit from a specific treatment and would achieve a better clinical outcome in response to a specific treatment.

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SugarCone Biotech

MAY 28, 2019

A study, published in 2005, suggested that chloroquine could prevent SARS (the older virus) from infecting cells kept in culture. [2] It appears to also be true of the approval of aducanumab for the treatment of Alzheimer’s Disease (AD). In contrast, a weak hypothesis generates predictions that fail more often than not. Stay tuned. [1]

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New Drug Approvals

SEPTEMBER 7, 2024

Refer to WO 2004101742 A2, US 2005/0143320 Al, US 2006/0014821 Al, US 2009/0137818 Al, WO 2013049382 A2, WO 2013166319 A1, WO2018042343, WO2018023054, WO 2022013684, WO 2021252644, WO2022020711, WO 2022020242, US 11,174,231 B1, US 11,124,497 B1, WO 2005113580, and WO2006061714).

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Metabolite Tales Blog

MARCH 1, 2023

9 The evidence here is that treatment with P450 inhibitors removed the toxic effects seen in the compounds of interest. Thiazoles are more interesting because thio-amides and thio-ureas are all potential structural alerts and the formation can be linked to bioactivation of thiazoles. 2009, 41, 157-167 [link] 19 Molecules.

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The Pharma Data

DECEMBER 21, 2020

“The recent results from our NAVIGATOR trial were impressive, both in terms of the overall clinical data and the reduction in exacerbation rate with tezepelumab treatment, and we continue to work with AstraZeneca on planned regulatory filings in 2021. 2005; 172: 149-160. Am J Respir Crit Care Med. Eur Respir J.

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The Pharma Data

DECEMBER 15, 2020

Critical Path Institute (C-Path) is an independent, nonprofit organization established in 2005 as a public and private partnership. With the right treatment, knowledge and support people living with diabetes can lead a long, full and healthy life. About Critical Path Institute. There is currently no known cure for any type of diabetes.

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