2006 Metabolic Stability Process Chemistry Therapies 
Metabolite Tales Blog
JULY 5, 2023
Not only this, the reduction in rotatable bonds and consequent reduction in susceptibility to metabolism is an additional benefit [4]. A combination therapy of glecaprevir and pibrentasvir has recently been implicated in a case of liver injury. Journal of Medicinal Chemistry 62 (21), 9418-9437. Balazs et al., Nagasaka et al.,
Metabolite Tales Blog
JULY 5, 2023
Not only this, the reduction in rotatable bonds and consequent reduction in susceptibility to metabolism is an additional benefit [4]. A combination therapy of glecaprevir and pibrentasvir has recently been implicated in a case of liver injury. Journal of Medicinal Chemistry 62 (21), 9418-9437. Balazs et al., Nagasaka et al.,
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