2006 Process Chemistry Therapies Trials 
Metabolite Tales Blog
JULY 5, 2023
Still, of the 34 macrocycles currently in clinical trials, only 18% are de novo designed. A combination therapy of glecaprevir and pibrentasvir has recently been implicated in a case of liver injury. Journal of Medicinal Chemistry 62 (21), 9418-9437. Balazs et al., Drug Hunter article, June 2023. 20 (March 20, 2014).
Metabolite Tales Blog
JULY 5, 2023
Still, of the 34 macrocycles currently in clinical trials, only 18% are de novo designed. A combination therapy of glecaprevir and pibrentasvir has recently been implicated in a case of liver injury. Journal of Medicinal Chemistry 62 (21), 9418-9437. Balazs et al., Drug Hunter article, June 2023. 20 (March 20, 2014).
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