2007 Cell Biology Drugs Pharmacokinetics 
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NOVEMBER 1, 2023
Notably, it has been shown that LPA is a cell motility factor and inhibition of ATX results in a decrease of cellular invasion through a reduction of LPA concentration in the surrounding fluids in vitro. Andrew McCarthy Andrew is a Team Leader at EMBL Grenoble since 2007. The Journal of Cell Biology. 2017;2017:1–15.
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JANUARY 9, 2024
As such, it has been proposed that inhibiting CDK7 would provide a potent means of inhibiting cell cycle progression, which may be especially relevant given that there is compelling evidence from gene knockout studies in mice for lack of an absolute requirement for CDK2, CDK4 and CDK6 for the cell cycle at least in most cell types (M alumbres et al.,
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