Drug Target Review

NOVEMBER 27, 2023

This approach is highly targeted, as STRIs selectively inhibit the translation of a specific network of disease-causing proteins without affecting the broader cellular machinery. By directly inhibiting the translation of disease-causing proteins, STRIs offer a novel strategy to overcome resistance mechanisms. He received his B.S.

Molecular Biology 86

Molecular Biology Therapies Pharmaceuticals Treatment 86

Drug Target Review

JUNE 19, 2024

There are many opportunities to address conditions of the eye, such as retinitis pigmentosa, dry age-related macular degeneration or any of the hundreds of inherited retinal diseases. He received a BS in biology from Boston College, a masters in biochemistry and molecular biology from the University of California, Santa Barbara, and an M.B.A.

Therapies 84

Therapies Small Molecule Pharmaceutical Companies Molecular Biology 84

Broad Institute

APRIL 25, 2024

He started to imagine how the deadly and contagious disease, if confirmed, might spread to half the city’s population. Eight of the 20 patients died, but the spread of the disease in Nigeria stopped there. Blood and urine samples from the man were waiting for Happi in his lab. Happi felt chilled. They called the idea Sentinel.

Virus 132

Virus Hospitals Disease Government 132

Dark Matter Blog

JULY 16, 2021

The only subject in school that held my interest was biology. As soon as I learned about DNA and RNA, I wanted to be a molecular biologist. I wanted to use molecular biology to create drugs. Synta was focused on small molecule drug discovery and development in oncology and inflammatory diseases.

Small Molecule 52

Small Molecule RNA Clinical Trials DNA 52

Drug Discovery World

MAY 12, 2023

José Mejía Oneto , PhD, Founder and CEO at Shasqi, discusses the potential of chemistry to engineer biology to improve the effectiveness of human therapeutics and revolutionise the treatment of disease. This simple and elegant chemistry concept has the potential to revolutionise how we treat disease. 2007 Oct 23;104(43):16793-7.

Organic Chemistry 130

Organic Chemistry Therapies Immune Response Treatment 130

Codon

MARCH 12, 2023

I recently asked for recommendations of “classic” papers in molecular biology. And a Phase I study for three patients with late-onset Pompe disease, a rare genetic disorder that causes glycogen to build up inside of cells and causes the heart and skeletal muscles to slowly break down, also looks promising.

DNA 52

DNA Engineering RNA Therapies 52

Codon

AUGUST 10, 2023

Journal of Molecular Biology (1961). Link Mathematical modeling and synthetic biology , by Chandran D. Drug Discovery Today: Disease Models (2008). Link Graphic Notations →Synthetic Biology Open Language Visual: An Open-Source Graphical Notation for Synthetic Biology , by Quinn J. BMC Biology (2019).

DNA 98

DNA Cell Biology Molecular Biology Engineering 98