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Defense-Forward Biosecurity

Codon

Allison Berke makes the case for real-time DNA sequencing and AI tools to detect pathogens before they spread widely. Reading DNA The first step in detecting a novel pathogen is recognizing it as an anomaly amidst a noisy background of other material. After copying the DNA to form a big pool, each piece is sequenced.

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CRISPR to Reveal How “Water Bears” (Tardigrades) Survive Extreme Environments

PLOS: DNA Science

Tardigrades were obvious choices for animals to observe in space, surviving for awhile the vacuum, lack of gravity, extreme temperatures, and radiation of low-Earth orbit of NASA’S FOTON-M3 mission in 2007. ” The post CRISPR to Reveal How “Water Bears” (Tardigrades) Survive Extreme Environments appeared first on DNA Science.

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TEST: The Stanley Center for Psychiatric Research - History

Broad Institute

TEST: The Stanley Center for Psychiatric Research - History By Maria Nemchuk August 25, 2023 Breadcrumb Home TEST: The Stanley Center for Psychiatric Research - History The Stanley Center was launched in 2007 with transformative support from the philanthropists Ted and Vada Stanley, through the Stanley Medical Research Institute.

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Key considerations before commencing cell line development

Drug Target Review

After binding, the transposase enzyme will excise the flanked section of DNA (termed the transposon) and insert it into sites in the genome at specific target sequences. An example of the former includes a report in the journal Nature of a new tool that can increase the amount of DNA that can be inserted using CRISPR-Cas9 technology.

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How Breast Cancer Reunited Six High School Friends

PLOS: DNA Science

We watched the special Bandersnatch episode of Black Mirror and played the game of choosing a story path and alternate endings, which inspired my DNA Science post from exactly a year ago comparing the game to a journey with breast cancer. The post How Breast Cancer Reunited Six High School Friends appeared first on DNA Science.

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The evolution of cell therapy to address unmet medical needs

Drug Target Review

The other powerful benefit is that our cell lines can become any of the cell types of the human body – these cells have within their DNA the capability to become any of the more than 200 human cell types which you might want to manufacture. This provides some regulatory advantages, and of course, significant cost advantages.

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Genetic Signature for Drug Addiction Revealed in New Analysis of More Than A Million Genomes

PLOS: DNA Science

“RFLPs” are sites in a DNA sequence where a bacterial enzyme, called a restriction enzyme, cuts. See The Age of the Pangenome Dawns , here at DNA Science from a few months ago.) As the first genomes were being sequenced, researchers began identifying the sites where the 4 DNA bases vary among individuals.

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