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The evolution of cell therapy to address unmet medical needs

Drug Target Review

The mission of Lineage Cell Therapeutics is to deliver on some of the early promises of cell therapy. Cell therapy as a concept is a wonderful idea, but many of the early efforts never generated the kind of clinical data that gets people excited and leads to new medicines. In some cases, cell therapy can be curative for the patient.

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The role of STRIs in cancer

Drug Target Review

By directly interfering with the eIF4F complex, eFFECTOR’s STRIs provide a promising avenue for disrupting the core mechanisms of cancer, offering the potential to improve patient outcomes and overcome the limitations of traditional cancer therapies. Dr Worland has served on the board of directors of Tracon Pharmaceuticals, Inc.,

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A Look Back

Dark Matter Blog

The only subject in school that held my interest was biology. As soon as I learned about DNA and RNA, I wanted to be a molecular biologist. I wanted to use molecular biology to create drugs. I had a first-hand role in raising money from Wall Street by being part of an IPO roadshow as Synta went public in 2007.

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The Nobel Prize winning power of click chemistry

Drug Discovery World

The toxicities associated with cancer therapies are significant. These side effects not only contribute to a lower functional status and quality of life but can also lead to delays and discontinuation of therapy that decrease treatment effectiveness and increase the morbidity and mortality of the disease 3. 2001, 40, 2004-2021.

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Codon: Notes on Progress #2

Codon

Related news : “More than 200 people have been treated with experimental CRISPR therapies.” The landmark paper enabled revolutions in insulin biomanufacturing, CAR-T therapies, and the bioproduction of most modern vaccines; in other words, much of what we take for granted today. Lots of gene therapy data this week.

DNA 52
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The Codon Guide to Synthetic Biology

Codon

Journal of Molecular Biology (1961). Link (Golden Gate assembly) Other Basic Methods & Cloning →Basic Methods in Cellular and Molecular Biology , by multiple authors. Link Molecular Cloning Techniques , by AddGene. Molecular Biology of the Cell, 4th Edition. BMC Systems Biology (2007).

DNA 98
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The Codon Guide to Synthetic Biology

Codon

Journal of Molecular Biology (1961). Link (Golden Gate assembly) Other Basic Methods & Cloning →Basic Methods in Cellular and Molecular Biology , by multiple authors. Link Molecular Cloning Techniques , by AddGene. Molecular Biology of the Cell, 4th Edition. BMC Systems Biology (2007).

DNA 52