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2007; Ganuza et al., As a TFIIH subunit, CDK7 phosphorylates the CTD (Carboxy-Terminal-Domain) of the largest subunit of RNA polymerase II (pol II). In addition to CDK7, other CDKs have been reported to phosphorylate and regulate RNA pol (II) CTD. Mar 23;25(6):839-50. May 30; 31(11): 2498-510, 2012). 13, 261-91, 1997).
.” In 1974, Wolfram Ostertag , a German geneticist at the Max Planck Institute, explored whether zidovudine could block retroviruses , which carry RNA, and use a reverse transcriptase enzyme to convert it into DNA before integrating into the host genome.
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