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puts an end to the previous mandate that all drugs need to be tested on animals prior to human clinical trials. Prior to this European Union Parliament, in 2021, voted for animaltesting phase out. The US FDA Modernisation Act 2.0.,
Human derived induced pluripotent stem cells (hiPSCs) have revolutionised research and are increasingly used for toxicology screening and disease modelling. 2008 Mar;153 Suppl 2(Suppl 2):S1-209. Using stem cell-derived neurons in drug screening for neurological diseases. Guide to Receptors and Channels (GRAC), 3rd edition.
The PPPR framework governs the authorization, sale, and use of PPPs, establishing a pre-market approval process for active substances – the pesticide components which control pests, weeds, and plant diseases – and for synergists and safeners before they can be allowed for use in PPPs.
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