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Advanced 3D cell-based technologies

Drug Target Review

First developed in 2008, by Toshiro Sato, Hubrecht Institute at Utrecht University, these structures range from mini-brains to mini-guts with varied applicability from drug discovery to personalised medicine. From 3D cell culture to organs-on-chips. Trends in Cell Biology. 2010;328(5986):1662-8. 2011;21(12):745-54.

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Fast Biology

Codon

In 2008, researchers at UC Berkeley devised an ingenious solution. Credit: Rob Phillips and Ron Milo, Cell Biology by the Numbers. They are a starting point for experiments, allowing one to evaluate what is possible with biology versus what ought to remain consigned to the realms of science fiction.

RNA 98
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Discovering an Antimalarial Drug in Mao’s China

Codon

When Louis Miller, now Chief of Malaria Cell Biology at the NIH, attended a malaria conference in Shanghai in 2008, he asked: Who discovered artemisinin? Few journal articles were written about the project using her (or anyone’s) name before 2010. Nobody had an answer.

Drugs 129
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Women in Stem with Vicky Marsh Durban

Drug Target Review

I don’t think that it’s harder for women to enter careers in STEM, at least not in the scientific field—cell biology—that I have predominantly worked in. Vicky’s journey started with a PhD from Cardiff University in 2008, focusing on cancer genetics.

Doctors 59
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A Defense of Peer Review

Codon

However, I think caution is warranted when drawing sweeping conclusions from these studies because they were each conducted over only a decade (between 1998 and 2008) in just two medical journals (the British Medical Journal and The Annals of Emergency Medicine.) These numbers are quite low and do not inspire confidence.

Science 93
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Precision Medicine in the Genomic Era

DrugBank

9 , 477–485 (2008). Network expansion of genetic associations defines a pleiotropy map of human cell biology. 12 , 713230 (2021).  Slatkin, M. Linkage disequilibrium — understanding the evolutionary past and mapping the medical future.  The 1000 Genomes Project Consortium et al.  McInnes, G.,

Disease 88
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The Codon Guide to Synthetic Biology

Codon

Nature Reviews Molecular Cell Biology (2009). Link The second decade of synthetic biology: 2010–2020 , by Meng F. & Link Synthetic biology in mammalian cells: next generation research tools and therapeutics , by Lienert F. Nature Reviews Molecular Cell Biology (2014). . & Weiss R.

DNA 91