Codon
FEBRUARY 13, 2025
One study from 2008 (also from the Baker lab) reported de novo enzyme catalysts for Kemp elimination — a reaction that opens up a benzisoxazole ring — by running molecular dynamics simulations to sieve through possible designs. They synthesized DNA encoding each protein variant, expressed the proteins in E.
Drug Target Review
NOVEMBER 13, 2023
The instructions to form a cell are encoded in DNA strands, wrapped in proteins and RNA, and wound together into a 3D structure called chromatin. Another finding was that regulatory T cells had distinct chromatin architecture features called DNA loops. Nature reviews immunology [Internet] 2008 July [2023 November 10]; 8:523-32.
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Codon
AUGUST 27, 2024
Allison Berke makes the case for real-time DNA sequencing and AI tools to detect pathogens before they spread widely. Reading DNA The first step in detecting a novel pathogen is recognizing it as an anomaly amidst a noisy background of other material. After copying the DNA to form a big pool, each piece is sequenced.
Codon
JUNE 11, 2024
And unlike traditional DNA sequencers, which parse genetic material by breaking it up into fragments and interpreting it chunk-by-chunk, a nanopore device unspools a long strand of DNA and reads it all at once. A scientist can isolate DNA and load up a flow cell in fifteen minutes. Nanopore devices work incredibly fast.
PLOS: DNA Science
MARCH 21, 2024
The history of gene therapy for MLD is compelling – DNA Science covered it for Rare Disease Day in 2021, here. Liviana was born in January 2008 in Omaha, Nebraska, and diagnosed with MLD in December 2010. That would enable identification of children before symptoms begin. Developmental milestones ebbed and vanished.
PLOS: DNA Science
AUGUST 22, 2024
When Crichton died of cancer in 2008, he left behind a staggering trove of research about an eruption of Mauna Loa on the Big Island of Hawaii. ” The explanation continues, and here’s where it ceases to make sense, to anyone who knows anything about DNA, genes, and genomes. The DNA double helix is exquisitely symmetrical.
BMG Labtech
DECEMBER 20, 2024
Whether it is determining concentrations of molecules like proteins or DNA, looking at enzyme kinetics for crucial reactions, or measuring something as fundamental as cell growth, you will find references to absorbance or optical density measurements. Online corrected version: (2008) "Absorbance". the "Gold Book") (1997).
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