Drug Target Review

NOVEMBER 13, 2023

The instructions to form a cell are encoded in DNA strands, wrapped in proteins and RNA, and wound together into a 3D structure called chromatin. Another finding was that regulatory T cells had distinct chromatin architecture features called DNA loops. Nature reviews immunology [Internet] 2008 July [2023 November 10]; 8:523-32.

Government 104

Government DNA RNA Regulations 104

Codon

JUNE 11, 2024

And unlike traditional DNA sequencers, which parse genetic material by breaking it up into fragments and interpreting it chunk-by-chunk, a nanopore device unspools a long strand of DNA and reads it all at once. A scientist can isolate DNA and load up a flow cell in fifteen minutes. Nanopore devices work incredibly fast.

DNA 85

DNA Engineering RNA Small Molecule 85

Codon

FEBRUARY 20, 2024

Thanks to decades of progress in molecular sequencing technologies, it is simple to read out the order of nucleotides in a DNA sequence, for example, or to quantify messenger RNAs as they are made by a cell. In 2008, researchers at UC Berkeley devised an ingenious solution. But again, how do we know? This paper is one example.

RNA 98

RNA DNA Engineering Cell Biology 98

BMG Labtech

DECEMBER 20, 2024

Whether it is determining concentrations of molecules like proteins or DNA, looking at enzyme kinetics for crucial reactions, or measuring something as fundamental as cell growth, you will find references to absorbance or optical density measurements. Online corrected version: (2008) "Absorbance". the "Gold Book") (1997).

DNA 52

DNA Science Laboratories RNA 52

New Drug Approvals

SEPTEMBER 29, 2024

gingivalis DNA was detected in postmortem cortices from people with AD and healthy controls, and in CSF of AD patients ( Jan 2019 news on Dominy et al., gingivalis infection led to the appearance of bacterial DNA in the brain, increased brain Aβ42 production, neuroinflammation, and hippocampal degeneration. Epub 2008 Dec 29 PubMed.

Small Molecule 62

Small Molecule DNA Disease Trials 62

Codon

AUGUST 27, 2024

Allison Berke makes the case for real-time DNA sequencing and AI tools to detect pathogens before they spread widely. Reading DNA The first step in detecting a novel pathogen is recognizing it as an anomaly amidst a noisy background of other material. After copying the DNA to form a big pool, each piece is sequenced.

DNA 99

DNA Laboratories Hospitals Virus 99

Codon

AUGUST 10, 2023

Nature Reviews Molecular Cell Biology (2008). Drug Discovery Today: Disease Models (2008). Technologies DNA Sequencing →DNA sequencing at 40: past, present and future , by Shendure J. Link DNA Cost and Productivity Data, aka "Carlson Curves" , by Carlson R. & Shamir R. Artificial Life (2018). PNAS (2013).

DNA 98

DNA Cell Biology Molecular Biology Engineering 98