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Driving Toward Nanopores

Codon

And unlike traditional DNA sequencers, which parse genetic material by breaking it up into fragments and interpreting it chunk-by-chunk, a nanopore device unspools a long strand of DNA and reads it all at once. A scientist can isolate DNA and load up a flow cell in fifteen minutes. Nanopore devices work incredibly fast.

DNA 85
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AI in gene delivery vector discovery and design

Drug Target Review

Genome engineering and gene therapies that manipulate DNA sequences in cells have driven a biotechnological revolution over the past decade. 1 Adeno-associated virus (AAV) vectors are the leading platform for in vivo gene delivery for the treatment of various human diseases. Engineering adeno-associated virus vectors for gene therapy.

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Michael Crichton and James Patterson’s “Eruption” is Riveting, but with a Shaky Genetic Foundation

PLOS: DNA Science

When Crichton died of cancer in 2008, he left behind a staggering trove of research about an eruption of Mauna Loa on the Big Island of Hawaii. ” The explanation continues, and here’s where it ceases to make sense, to anyone who knows anything about DNA, genes, and genomes. The DNA double helix is exquisitely symmetrical.

DNA 68
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Defense-Forward Biosecurity

Codon

Allison Berke makes the case for real-time DNA sequencing and AI tools to detect pathogens before they spread widely. Reading DNA The first step in detecting a novel pathogen is recognizing it as an anomaly amidst a noisy background of other material. After copying the DNA to form a big pool, each piece is sequenced.

DNA 99
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“The Dressmaker’s Mirror: Sudden Death, Genetics, and a Jewish Family’s Secret” Traces a Long-ago Tragic Accident to an Inherited Heart Disease

PLOS: DNA Science

Karen died on November 16, 2008 – coincidentally, the same date that Dr. Liebman’s father had died 28 years earlier, at age 66, from a presumed heart attack. Dr. McNally checked Diane’s DNA for new mutations as they were discovered. Her doctor said this was because she was 6 months pregnant. But still no hits.

Disease 80
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Barcoding Brains

Codon

Metagenomics, for example, allows scientists to build extensive reference libraries of DNA for use in everything from the creation of vital medicines to CRISPR tools. .” Buried in this mouthful is a crystalline and clever idea; to tag each neuron in the brain with its own ID so that images can be more easily stitched together.

Research 100
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Blackburn – That’s Just Plain Wrong

Drug & Device Law

vii) Changes solely affecting a natural product, a recombinant DNA-derived protein/polypeptide, or a complex or conjugate of a drug substance with a monoclonal antibody for the following: (A) Changes in the virus or adventitious agent removal or inactivation method(s); (B) Changes in the source material or cell line ; and. 4 (FDA Jan.

FDA 59