Metabolism of 2022 FDA approved small molecule drugs PART 2
Metabolite Tales Blog
APRIL 4, 2023
Deuteration at this position was found to block generation of a less selective primary amide metabolite in vivo and increase metabolic stability. Insights into drug metabolism by cytochromes P450 from modelling studies of CYP2D6-drug interactions. 2008 Mar;153 Suppl 1(Suppl 1):S82-9. Br J Pharmacol. Acta Pharm Sin B.
52 
Let's personalize your content