Perficient: Drug Development

OCTOBER 4, 2023

CLIENT An American multinational corporation that develops medical devices, pharmaceuticals, and consumer packaged goods. PROJECT BACKGROUND Since 2008, Perficient has delivered multiple infrastructure platforming, commerce, and management consulting projects for this multinational corporation.

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The Pharma Data

DECEMBER 17, 2020

With years of pharmaceutical expertise to her credit, Dr. Johnson first garnered inspiration for her professional future during her formative years. After relocating to Montgomery, Alabama, she retained this title and its responsibilities at Jackson Hospital from 2008 to 2015. About Marquis Who’s Who® Since 1899, when A.

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The Pharma Data

MARCH 17, 2021

Clyburn joined Merck in 2008 and has had responsibility for numerous global pharmaceutical franchises, including diabetes, cardiovascular and women’s health, as well as leadership of marketing and sales teams. Clyburn became chief commercial officer for Human Health in January 2019.

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New Drug Approvals

SEPTEMBER 8, 2024

2007.05.007 Drug Discovery, Johnson and Johnson Pharmaceutical Research and Development, LLC, 8 Clarke Drive, Cranbury, NJ 08512, USA Scheme 1. Retrieved 5 September 2024. ^ Billin AN (October 2008). Seladelpar works to block bile acid synthesis. 6] compound 3r [PMID: 17524639] Bioorg Med Chem Lett. 2007 Jul 15;17(14):3855-9.

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The Pharma Data

APRIL 10, 2021

Maria and William have diverse backgrounds spanning medical research, pharmaceuticals, business, not-for profit boards and public health. From March 2008 to November 2012 she served as President and as a member of the board of directors of the Albert and Mary Lasker Foundation, which supports biomedical research.

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The Pharma Data

JULY 22, 2021

Teva Pharmaceutical Industries Ltd. Sven joined Teva as general manager, Germany, in 2008. NYSE and TASE: TEVA) today announced changes to its leadership team. Sven became Executive Vice President, Global Marketing & Portfolio in 2017 and assumed responsibility for international markets commercial in 2021. Sven received his Ph.D.

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The Pharma Data

JUNE 28, 2021

“The filing of this application in the US is an important step in helping to address the burden of venous thromboembolism and provide doctors with body weight-based dosing options in pediatric patients,” said Dr Christian Rommel, Head of Research and Development and Member of the Executive Committee at Bayer Pharmaceuticals.

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The Pharma Data

MAY 15, 2023

Before joining Nestlé he served as CFO at Takeda Pharmaceuticals, one of the largest publicly listed companies in Japan, between 2013 and 2015, and CFO at Millicom, a NASDAQ listed global mobile phone operator based in Luxembourg, between 2008 and 2013. François-Xavier Roger, Chief Financial Officer of Nestlé S.A.,

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The Pharma Data

NOVEMBER 25, 2020

Vifor Pharma Group is a global pharmaceuticals company. The company is a partner of choice for pharmaceuticals and innovative patient-focused solutions. The company develops, manufactures and markets pharmaceutical products for precision patient care. Am J Clin Nutr. 2015;102(6):1585-94. World Health Organization.

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The Pharma Data

AUGUST 19, 2021

Gorsky’s leadership has been oncology, with the Company’s sales in this area growing from approximately $2 billion in 2011 to over $12 billion in 2020, while acquisitions have included Actelion, the largest in the Company’s history, which significantly expanded Johnson & Johnson’s Pharmaceutical segment portfolio of rare-disease treatments.

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The Pharma Data

DECEMBER 17, 2020

Hartfield previously served as CEO of Vitae Pharmaceuticals prior to its acquisition by Allergan. X4 Pharmaceuticals – Diego Cadavid was named chief medical officer of Boston-based X4 Pharmaceuticals. Karydas is chief financial officer at Syndax Pharmaceuticals. Sucampo Pharmaceuticals and Histogenics Corporation.

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The Pharma Data

MARCH 2, 2021

As a world-leading, research-driven pharmaceutical company, more than 51,000 employees create value through innovation daily for our three business areas: Human Pharma, Animal Health, and Biopharmaceutical Contract Manufacturing. About Gubra.

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Metabolite Tales Blog

JANUARY 26, 2023

Since CYP2D6 displays a genetic polymorphism, resulting in large interindividual and ethnic differences, pharmaceutical companies have a motivation to design drug candidates that avoid metabolism by this CYP, something that seems to have come to fruition in this set of new drug approvals. References Iversen et al., 2022; 131(5): 311- 324.

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The Premier Consulting Blog

APRIL 27, 2023

Then, in 1997, the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) formed the ICH M8 Expert Working Group/Implementation Working Group (EWG/IWG). the current default version internationally, was established in 2008. and around the world, and eCTD v3.2.2, FDA eCTD v4.0

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Drug Target Review

SEPTEMBER 26, 2023

Gaps and challenges in nonclinical assessments of pharmaceuticals: An FDA/CDER perspective on considerations for development of new approach methodologies. 2008 Mar;153 Suppl 2(Suppl 2):S1-209. Human neuronal cells: Possibilities in drug safety testing and beyond Avila AM, Bebenek I, Mendrick DL, Peretz J, Yao J, Brown PC. Rockley KL.

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The Pharma Data

NOVEMBER 5, 2020

X4 Pharmaceuticals – Art Taveras was named CSO of Cambridge, Mass.-based Prior to that, Taveras was vice president of Small Molecule Drug Discovery and CMC Development at Biogen Idec, and Alantos Pharmaceuticals, which was acquired by Amgen in 2007. Venugopal most recently served as executive director at Intercept Pharmaceuticals.

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The Pharma Data

AUGUST 9, 2020

About Roche Roche is a global pioneer in pharmaceuticals and diagnostics focused on advancing science to improve people’s lives. Moreover, for the eleventh consecutive year, Roche has been recognised as one of the most sustainable companies in the Pharmaceuticals Industry by the Dow Jones Sustainability Indices (DJSI).

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Agency IQ

JUNE 21, 2024

Regulation (EC) No 1234/2008 (Variations Regulation) provides the procedures for implementing the different types of variations. That same year, the Pharmaceutical Strategy for Europe called for a revision of the Variations Regulation and an evaluation of the existing legislation.

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Molecule Blog

AUGUST 13, 2021

Announcing the first biopharma IP-NFT Transaction Funding the first longevity research project by utilizing intellectual property NFTs in the pharmaceutical space Summary The vote has passed, the decision is made: The Scheibye-Knudsen Lab will be the first research organisation to fund their longevity research via an IPNFT.

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The Pharma Data

AUGUST 16, 2020

When my daughter was diagnosed with NMOSD in 2008, there were no approved treatment options, and a critical lack of resources and understanding for people living with this disabling disorder. Roche is a global pioneer in pharmaceuticals and diagnostics focused on advancing science to improve people’s lives. About Roche.

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Metabolite Tales Blog

MAY 12, 2023

Now >20% of all commercialised medicines in the pharmaceutical industry contain a fluorine atom [2]. References [1] Metabolic and Pharmaceutical Aspects of Fluorinated Compounds. Molecular Pharmaceutics 2020 17 (8), 3106-3115, [link] [10] Probing Mechanisms of CYP3A Time-Dependent Inhibition Using a Truncated Model System.

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Codon

APRIL 9, 2024

When Louis Miller, now Chief of Malaria Cell Biology at the NIH, attended a malaria conference in Shanghai in 2008, he asked: Who discovered artemisinin? Medical research groups were joined by pharmaceutical companies, chemical and spice factories, botany institutes, and insect science institutes. Nobody had an answer.

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New Drug Approvals

SEPTEMBER 29, 2024

In January 2023, Quince put out word that it had sold Cortexyme’s legacy small molecule protease inhibitor portfolio to Lighthouse Pharmaceuticals, a company co-founded by a former Cortexyme CEO ( press release ). Epub 2008 Dec 29 PubMed. The company changed its name to Quince, and its focus to bone disease. Infect Immun.

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Agency IQ

NOVEMBER 27, 2023

Many posted comments came from professional pharmacy organizations, trade groups like the Pharmaceutical Research and Manufacturers of America (PhRMA) , and pharmaceutical companies, such a Eli Lilly , Novo Nordisk and Merck.

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Agency IQ

OCTOBER 6, 2023

According to the Substance Abuse and Mental Health Services Administration (SAMHSA), “between 2008 and 2015, amphetamine-related hospitalizations more than tripled, increasing from 55,447 instances to 206,180. While stimulant use disorder is increasing, there are currently no FDA-approved medications.

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The Pharma Data

AUGUST 17, 2021

Since launch in 2008, more than 86 million patients have been treated. by Janssen Pharmaceuticals, Inc. Janssen Research & Development, LLC and Janssen Pharmaceuticals, Inc. are part of the Janssen Pharmaceutical Companies of Johnson & Johnson). Xarelto is marketed outside the U.S. by Bayer and in the U.S.

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Agency IQ

JULY 5, 2023

Section 2008 Improved Consumer Confidence Reports amended the Safe Drinking Water Act section 1414(c)(4) to revise requirements for Consumer Confidence Reports (CCR). Finally, the proposed rule makes technical revisions to remove outdated references associated with section 404(g) regulations. The Agency is now reconsidering that action.

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Agency IQ

DECEMBER 15, 2023

Circuit granted EPA a voluntary remand in 2008 for the Agency to re-evaluate the MACT floors established in 1995 based on the D.C. The Gasoline Distribution NESHAP, subparts R and BBBBBB, were promulgated pursuant to section 112(d) of the Clean Air Act(CAA) on December 14, 1994, and January 10, 2008, respectively. EPA, 358 F.3d

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Agency IQ

JUNE 16, 2023

Section 2008 Improved Consumer Confidence Reports amended the Safe Drinking Water Act section 1414(c)(4) to revise requirements for Consumer Confidence Reports (CCR). EPA recently reclassified several areas as Severe nonattainment areas for the 2008 ozone NAAQS. These areas include Dallas-Fort Worth, TX, Denver-Boulder-Greeley-Ft.

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Agency IQ

SEPTEMBER 29, 2023

The Gasoline Distribution NESHAP, subparts R and BBBBBB, were promulgated pursuant to section 112(d) of the Clean Air Act (CAA) on December 14, 1994, and January 10, 2008, respectively. EPA recently reclassified several areas as Severe nonattainment areas for the 2008 ozone NAAQS.

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Common Sense for Drug Policy Blog

NOVEMBER 15, 2024

Piperazines first appeared in 2000 but saturated the market from 2008–2013, when these compounds were detected in about one-quarter (24 %) of drug items. Pharmaceuticals (5 %) and supplements (4 %) appeared consistently as adulterants, but their prevalence has generally declined over time. 2024.112467.

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New Drug Approvals

APRIL 9, 2025

Chemical synthesis The synthesis of gepotidacin has been described in two patents in 2008 and 2016 and comprises 11 steps (Fig. WO2008128942A1 References: GLAXO GROUP LIMITED WO2008/128942, 2008, A1Yield:- Steps: Multi-step reaction with 12 steps 1.1: Gepotidacin is derived from the analogue GSK299423 described by Bax et al. [9],

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Drug Target Review

NOVEMBER 27, 2024

11 Pharmaceutical companies are increasingly outsourcing due to resource and capacity constraints, the need for specialised expertise, and the flexibility outsourcing offers in project management. 2008 Aug 1;63(8):879–84. The global biomarker discovery outsourcing service market was estimated at $2.7 Food and Drug Administration.

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Alta Sciences

MARCH 4, 2025

The CCALC is a grassroots organization that was founded by several pharmaceutical industry members seeking clarity around the conduct of abuse and dependence potential assessments for novel drugs in development. This was in 2006, at a time when the FDA guidances on these topics had not yet been published.

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Drug Target Review

JANUARY 16, 2025

Their collaborative work continues to drive advancements in computational methods, offering new solutions to the intricate problems of preclinical pharmaceutical discovery through innovative predictive modelling techniques. Nature Reviews Drug Discovery , 7(7):608624, 2008. Pharmaceuticals , 16(7):996, 2023. Springer, 2019.

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New Drug Approvals

APRIL 5, 2025

Retrieved 2 January 2023. ^ “Trecondi (Link Medical Products Pty Ltd T/A Link Pharmaceuticals)” Therapeutic Goods Administration (TGA). Medexus Pharmaceuticals. “International nonproprietary names for pharmaceutical substances (INN). Reference Example 2 (repetition of Synthesis, No. 21 December 2022.

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Agency IQ

JANUARY 4, 2024

Circuit granted EPA a voluntary remand in 2008 for the Agency to re-evaluate the MACT floors established in 1995 based on the D.C. The EPA received a petition for reconsideration of the 2006 rulemaking and, in 2007, EPA announced its reconsideration of several aspects of the rule. EPA, 358 F.3d 3d 936 (D.C.

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