2008 Process Chemistry Virus 
Metabolite Tales Blog
JULY 5, 2023
However, more de novo designed molecules in this “beyond the Rule of 5 chemical space” have emerged, with the first in this class, plerixafor , approved in oncology in 2008. Journal of Medicinal Chemistry 62 (21), 9418-9437. link] [4] Macrocyclization via Ring-Closing Metathesis in Drug Discovery & Process Chemistry.
Metabolite Tales Blog
JULY 5, 2023
2] However, more de novo designed molecules in this “beyond the Rule of 5 chemical space” have emerged, with the first in this class, plerixafor , approved in oncology in 2008. Journal of Medicinal Chemistry 62 (21), 9418-9437. link] [4] Macrocyclization via Ring-Closing Metathesis in Drug Discovery & Process Chemistry.
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