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TACACICLIB, AUR-102, AURIGENE

New Drug Approvals

The present invention is directed to methods of preparation of compound of formula (I) that is useful for inhibiting Cyclin-dependent kinase 7 (CDK7) and for treating diseases or disorders mediated thereby. Recent genetic and biochemical studies have confirmed the importance of CDK7 for cell cycle progression (Larochelle.

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Women in STEM: An Inspiring Journey with Dr Jo Brewer

Drug Target Review

Because we are using cells as medicines, they’re living medicines that we hope that they become cancer treatments where it’s literally one dose and you’re done. When it comes down to cell biology itself, cells can do so many different things.

Therapies 115
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Precision Medicine in the Genomic Era

DrugBank

Out of the millions of genetic variants present in human populations, GWAS are designed to uncover those associated with specific traits or diseases. 9 Polygenic diseases are much more common, and thousands of genetic variants with very small effects could impact their phenotype.

Disease 87
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Codon Digest: CAR-T Therapy for Neuroblastoma

Codon

Read Longevity Heterogeneous aging across multiple organ systems and prediction of chronic disease and mortality. Read Cold temperature extends longevity and prevents disease-related protein aggregation through PA28γ-induced proteasomes. Nature Cell Biology. for its gene therapy for an inherited eye disease.

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Neurobiology & Organismal Biology

Broad Institute

in Physics from the University of Illinois at Urbana-Champaign in 2009. Through his comprehensive investigations, he strives to advance knowledge and identify potential therapeutic interventions for stress-related psychiatric disorders and neurodegenerative diseases. in Physics from Massachusetts Institute of Technology in 2009.

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The Codon Guide to Synthetic Biology

Codon

Nature Reviews Molecular Cell Biology (2009). Link The second decade of synthetic biology: 2010–2020 , by Meng F. & Link Synthetic biology in mammalian cells: next generation research tools and therapeutics , by Lienert F. Nature Reviews Molecular Cell Biology (2014). . & Weiss R.

DNA 91
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The Codon Guide to Synthetic Biology

Codon

Nature Reviews Molecular Cell Biology (2009). Link The second decade of synthetic biology: 2010–2020 , by Meng F. & Link Synthetic biology in mammalian cells: next generation research tools and therapeutics , by Lienert F. Nature Reviews Molecular Cell Biology (2014). . & Weiss R.

DNA 52