The Pharma Data

DECEMBER 22, 2020

Stress From Not Achieving Goals Tied to Worse Kidney Disease. from the University of Mississippi in Jackson, and colleagues explored the association between goal-striving stress (GSS) and RKFD among 2,630 African Americans using data from the Jackson Heart Study (2000 to 2004 and 2009 to 2013). Professional. TUESDAY, Dec.

Disease 52

Disease Research 52

The Pharma Data

OCTOBER 26, 2020

Rural Patients With Alzheimer Disease Have Shorter Survival. 26, 2020 — Rural Medicare beneficiaries with Alzheimer disease and related dementia (ADRD) spend more time in nursing homes, receive less home health care, and have shorter survival than their urban counterparts, according to a study published online Oct. Professional.

Nurses 52

Nurses Disease Hospitals Research 52

The Pharma Data

AUGUST 21, 2020

The injectable treatment also covers other forms of MS including clinically isolated syndrome and active secondary progressive disease. The US regulator originally approved the drug in 2009 for the treatment of chronic lymphocytic leukaemia as an intravenous infusion with a high dose that was administered by a healthcare provider.

FDA Approval 52

FDA Approval Disease FDA Drugs 52

Drug Target Review

FEBRUARY 9, 2024

These characteristics position ADSCs as promising candidates for addressing a wide range of medical conditions, from degenerative diseases to traumatic injuries. Is there a certain disease or condition that you believe stem cell therapy holds the most promise for?

Therapies 105

Therapies Immune Response Clinical Trials Treatment 105

PLOS: DNA Science

OCTOBER 17, 2024

FDA approved a treatment for type 3 of the ultra-rare genetic disease September 20. The quest has been ongoing for three decades, said Laurie Turner, Family Services Manager of the National Niemann-Pick Disease Foundation. The new drug is taken with miglustat , which FDA approved for use in NPD3 in 2009. million a year.

Disease 52

Disease FDA Approval Drugs Treatment 52

Broad Institute

OCTOBER 17, 2023

Deik moved to the Broad in 2009 and joined Clish as a biochemist in the Platform, where she also serves as lab manager. A lot of what we do at the Metabolomics Platform is look for early indicators of disease and use metabolomics to monitor disease progression. What do you do as a research scientist at Broad?

Research 98

Research Small Molecule Science Disease 98

Conversations in Drug Development Trends

FEBRUARY 22, 2023

Rare Disease Day on February 28th is a chance for rare disease communities to come together as one and join in conversation with stakeholders searching for treatments, raising money to support research, and changing the way healthcare and governments interact with patients. In my case, my daughter Iris has GM1 gangliosidosis.

Disease 52

Disease Clinical Trials Trials Treatment 52

Eye on FDA

JANUARY 26, 2022

The database tracks disease area, type of communications vehicle, whether or not the product had a boxed warning, whether or not it involved a Warning or Untitled Letter, whether it was a digital or traditional communications property and of course, the violations cited in the letter.

FDA 108

FDA Production Drugs Disease 108

The Pharma Data

DECEMBER 3, 2020

Shivani Bakre, from the University of Michigan in Ann Arbor, and colleagues conducted a retrospective cohort study involving 135,152 Medicare beneficiaries on long-term dialysis between 2009 and 2016. Trends in alignment to an ACO were compared to those of the general Medicare population.

Research 52

Research Disease 52

Eye on FDA

SEPTEMBER 28, 2022

Research that is currently underway spans a number of topics, including the use of animation in DTC promotion, the impacts of disease awareness and prescription drug promotion on television, the use of superimposed text in DTC promotion, to name a few. A full list can be found here.

Research 69

Research Pharmaceutical Companies FDA Production 69

New Drug Approvals

SEPTEMBER 29, 2024

gingivalis has been called a risk factor for Alzheimer’s disease ( Kanagasingam et al., gingivalis is associated with cardiovascular disease. In aged dogs with periodontal disease, ninety days of COR388 reduced oral bacterial load and gum pathology ( Arastu-Kapur et al., In human neurons grown in culture, P. and Europe.

Small Molecule 62

Small Molecule DNA Disease Trials 62

The Pharma Data

APRIL 28, 2022

These actions have the potential to significantly reduce disease and death from combusted tobacco product use, the leading cause of preventable death in the U.S., by reducing youth experimentation and addiction, and increasing the number of smokers that quit.

FDA 52

FDA Disease Production Regulations 52

The Pharma Data

SEPTEMBER 30, 2020

Roche eventually released its data in 2012, and based on this, Jefferson concluded that Tamiflu could reduce the duration of flu symptoms, as well as the number of symptomatic cases among infected people, but found it did not cut the risk of disease transmission or lower respiratory complications. billion on stockpiling the drug.

Government 52

Government Trials Disease Production 52

Drug Target Review

SEPTEMBER 26, 2023

Human derived induced pluripotent stem cells (hiPSCs) have revolutionised research and are increasingly used for toxicology screening and disease modelling. 2009 Sep;14(17–18):876–84. Using stem cell-derived neurons in drug screening for neurological diseases. Neurotoxicology. 2010 Aug;31(4):331–50. Drug Discov Today.

Drugs 111

Drugs FDA Disease Animal Testing 111

Drug Target Review

OCTOBER 17, 2024

While its involvement in the do-not-eat-me signal from cancer has inspired therapeutic development of this pathway for oncology, the function of the innate immune checkpoint we identified in 2009 1 extends to both innate and adaptive immune responses. 2009 Mar 5;323(5922):1722–5. The Lancet Infectious Diseases [Internet].

Immune Response 52

Immune Response Clinical Trials Trials Therapies 52

The Pharma Data

OCTOBER 9, 2021

Application utilizes extrapolation-based strategy across existing breadth of STELARA data in patients living with this chronic inflammatory disease. Vice President, Rheumatology Disease Area Leader, Janssen Research & Development, LLC. With this latest submission, we’re excited to work with the U.S.

Treatment 52

Treatment FDA Approval FDA Pharmaceutical Companies 52

The Pharma Data

DECEMBER 11, 2020

11, 2020 — Results from a long-term study of a gene therapy technique to prevent inherited mitochondrial disease show promise, researchers say. The researchers said the technique could break the cycle of disease passed from mother to baby through mutations in mitochondrial DNA (mtDNA). FRIDAY, Dec. in the small intestine.

Therapies 52

Therapies Clinical Trials Disease Trials 52

The Pharma Data

DECEMBER 10, 2020

Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report. from the Council of State and Territorial Epidemiologists in Atlanta, and colleagues examined the prevalence of COVID-19 deaths in the AI/AN population in light of disproportionate mortality experienced during the 2009 influenza A(H1N1) pandemic.

Disease 52

Disease Research 52

DrugBank

JUNE 27, 2023

Out of the millions of genetic variants present in human populations, GWAS are designed to uncover those associated with specific traits or diseases. 9 Polygenic diseases are much more common, and thousands of genetic variants with very small effects could impact their phenotype.

Disease 98

Disease Treatment Drugs Clinical Trials 98

The Pharma Data

DECEMBER 8, 2020

Overall, the vaccine protected against symptomatic disease in 70% of cases, according to a team led by researchers from Oxford University in England. TUESDAY, Dec. 8, 2020 — AstraZeneca’s COVID-19 vaccine is safe and effective, new data from late-stage trials shows. New data posted Tuesday on the U.S.

Vaccine 52

Vaccine Trials Immune Response RNA 52

The Pharma Data

DECEMBER 7, 2020

based clinical trials investigating interventions for high blood pressure between 2009-2018, just 52 were exclusively in Black people. While the numbers grew over that decade – from 3.9% (3 of 77 trials) in 2009 to 6.2% (9 of 146) in 2018 – the increase was not enough to be statistically significant.

Treatment 52

Treatment Clinical Trials Trials Doctors 52

The Pharma Data

JANUARY 20, 2021

More than 205,000 kids and teens have the disease, and cases are rising. children and teens with type 2 diabetes increased by 30% between 2001 and 2009, with cases growing among youth aged 10 and older. WEDNESDAY, Jan. 20, 2021 — Kids with diabetes can lead full, fun lives, but they have special needs. The number of U.S.

Doctors 52

Doctors Hospitals Treatment Disease 52

The Pharma Data

SEPTEMBER 30, 2020

He added that Texas and the Centres for Disease Control and Prevention are moving to “make sure that it is fixed as quickly as possible and to make sure that it never happens again.”. Between 2009 and 2018, there were only 34 infections reported in the US.

Disease 52

Disease 52

Codon

JULY 21, 2024

Of course, AA and P-line rats are not the only research animals bred for the study of disease. By doing so, researchers study pain, genetic disorders, the effect of drugs, and disease pathways in mammals that, while genetically similar to us, are not human beings. They are bred, incised, injected, and deprived.

Research 123

Research Engineering Disease Science 123

The Pharma Data

MARCH 17, 2022

The study found that adjuvant treatment with KEYTRUDA significantly improved disease-free survival (DFS), one of the dual primary endpoints, reducing the risk of disease recurrence or death by 24% compared to placebo (hazard ratio [HR]=0.76 [95% CI, 0.63-0.91]; 0.91]; p=0.0014) in patients with stage IB (? “We About EORTC.

Therapies 52

Therapies Clinical Trials Disease Treatment 52

The Pharma Data

AUGUST 1, 2021

In these trials, more patients treated with Saphnelo experienced a reduction in overall disease activity across organ systems, including skin and joints, and achieved sustained reduction in oral corticosteroid (OCS) use compared to placebo, with both groups receiving standard therapy. 7,8,9,10,11.

Trials 52

Trials Therapies Disease Treatment 52

Drug Target Review

FEBRUARY 28, 2024

Previously, Mr Ho served as a Senior Equity Research Analyst at Bank of America from 2006 to 2009 and an Equity Research Analyst at Piper Jaffray & Co. Human γδ TCR repertoires in health and disease. from 2003 to 2006, covering the biotechnology and life-science tools sectors. References Fichtner A, Ravens S, Prinz I.

Therapies 105

Therapies Engineering Molecular Biology Science 105

The Pharma Data

APRIL 24, 2021

The COVID-19 pandemic highlights the importance of robust health systems to respond to disease outbreaks and to control other deadly diseases such as malaria. Despite the tremendous progress made in combating malaria in the past two decades, one child still dies from the disease every two minutes.

Clinical Trials 52

Clinical Trials Treatment Trials Disease 52

The Pharma Data

APRIL 27, 2022

An increase in measles cases in January and February 2022 is a worrying sign of a heightened risk for the spread of vaccine-preventable diseases and could trigger larger outbreaks, particularly of measles affecting millions of children in 2022, warn WHO and UNICEF. Measles is more than a dangerous and potentially deadly disease.

Vaccine 52

Vaccine Disease Virus 52

Broad Institute

AUGUST 2, 2023

in Physics from Massachusetts Institute of Technology in 2009. The Sabatini Lab focuses on the development and regulation of synapses in the brain and the relationship of these processes to behavior and disease. Daniel Hochbaum Daniel Hochbaum Daniel Hochbaum, Harvard Medical School Daniel Hochbaum, Ph.D. earned his Ph.D.

Medical Schools 52

Medical Schools Disease Science International 52

The Pharma Data

MAY 17, 2023

“Following Benin’s and Mali’s success, trachoma remains endemic in 23 countries in WHO’s African Region, bringing us a step closer towards the elimination target for trachoma set in the road map for neglected tropical diseases 2021–2030.” The disease is caused by infection with the bacterium Chlamydia trachomatis.

Disease 40

Disease International Treatment 40

National Drug & Alcohol Research Centre Blog

MAY 30, 2022

The disease burden and tobacco smoking in Australia Tobacco smoking is the leading cause of preventable disease and death in Australia. In 2015-2016 it accounted for over 9% of the total disease burden, caused over 21,000 annual deaths and cost $136.9 billion in social costs per year.

Treatment 40

Treatment Disease International Trials 40

The Pharma Data

NOVEMBER 25, 2020

Vifor Pharma Group strives to help patients around the world with severe and chronic diseases lead better, healthier lives. Even without anemia, iron deficiency can be debilitating, exacerbate an underlying chronic disease and lead to increased morbidity and mortality 4. 2009 Oct 7; 15(37): 4638-4643. Qual Life Res.

International 52

International Pharmaceuticals Disease Pharmaceutical Companies 52

Drug Target Review

JUNE 29, 2023

I mean, I work on the immune system and that has all sorts of opportunities in oncology and autoimmune disease, but there are plenty of others in terms of diabetes control, looking into Alzheimer’s, Parkinson’s and others. Prior to joining Adaptimmune in 2009, Jo held positions at Avidex, Medigene and Immunocore.

Therapies 115

Therapies Science Production Cell Biology 115

The Premier Consulting Blog

OCTOBER 21, 2024

The FDA defines a serious condition as “a disease or condition associated with morbidity that has a substantial impact on day-to-day functioning.” This pathway has been used since 1992, benefiting both sponsors and patients in various disease areas including oncology, neurology, infectious disease, and rare disease.

Trials 52

Trials FDA Clinical Trials Disease 52

The Pharma Data

JUNE 18, 2021

First approval of a conjugate vaccine that helps protect against 20 serotypes responsible for the majority of invasive pneumococcal disease and pneumonia, 1,2,3,4,5,6,7 including seven responsible for 40% of pneumococcal disease cases and deaths in the U.S. Following today’s FDA approval, the U.S. Jansen, Ph.D.,

Vaccine 52

Vaccine FDA Approval FDA Disease 52

Broad Institute

OCTOBER 16, 2024

Chan School of Public Health, lauded Studier for how the technology has enabled strategies for infectious disease control. He has a humble, self-effacing demeanor, and yet he is great at pushing people to make bold bets and to try to make the impossible possible." In a video message, Melissa J.

Vaccine 64

Vaccine RNA Laboratories Molecular Biology 64