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Codon Digest: CAR-T Therapy for Neuroblastoma

Codon

.” This technology could be used to design protein therapeutics that can bind to, and “shut down,” harmful or misfolded proteins in living cells. Thousands of transcription factors — proteins that bind DNA and control gene expression — were studied in human cells. Bergs A.C.F.

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FDA’s Project Optimus: A new era in oncology drug dosing

Drug Target Review

Genetic factors Mutations or alterations in tumour DNA (eg, EGFR mutations in lung cancer or HER2 amplification in breast cancer) are key targets of precision medicine. Molecular factors Molecular markers, such as protein expression and signalling pathway activation, also guide therapy choices. J., & Jnne, P. Barker, A.