Molecular Design
OCTOBER 20, 2024
One way of doing this is to build models for predicting biological activity and other pharmaceutically relevant properties such as aqueous solubility, permeability and metabolic stability.
Metabolite Tales Blog
MARCH 1, 2023
2009, 41, 157-167 [link] 19 Molecules. 44, 797–814 [link] Take a look at our other blogs The post Metabolism of five membered nitrogen containing heterocycles appeared first on Hypha Discovery. 1997, 25, 863-872 [link] 17a Drug Metab. 1994, 22, 651-658 [link] 17b Drug Metab. 2020, 25, 4309 [link] 20 Drug Metab.
Molecular Design
MAY 11, 2019
Design decisions in lead optimization are typically supported by assays for a range of properties such as solubility, permeability, metabolic stability and off-target activity as well as pharmacokinetic studies.
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