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His T7 expression technology can be used to make large quantities of nearly any RNA or protein and has been for decades, and continues to be, a mainstay of biomedical research and pharmaceutical production. In 2020, scientists used the T7 platform to produce enough mRNA for COVID-19 vaccines to vaccinate millions of people in the U.S.
Nature Reviews Molecular Cell Biology (2009). Nature Biotechnology (2009). Link DNA Cost and Productivity Data, aka "Carlson Curves" , by Carlson R. Nature Methods (2009). Link Directed Evolution →Exploring protein fitness landscapes by directed evolution , by Romero P.A. & & Weiss R. & Ellis T.
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