New Drug Approvals

SEPTEMBER 13, 2024

14] Pharmacokinetics The oral bioavailability of aticaprant is 25%. [1] 2] It first appeared in the scientific literature in 2010 or 2011. [16] 21] In August 2017, it was announced that Cerecor had sold its rights to aticaprant to Janssen Pharmaceuticals. [22] 14] Pharmacokinetics The oral bioavailability of aticaprant is 25%.

Treatment 62

Treatment Clinical Trials Pharmacokinetics Pharmaceuticals 62

Drug Target Review

SEPTEMBER 19, 2023

The first successful chip adaptation to a lung model was first described in 2010 by Donald Ingber, a bioengineer at Wyss institute. The chips can be modelled with primary cells, IPS derived stem cells or patient derived cells and potentiates to unlock molecular mechanisms that drive the disease pathophysiology, holding a greater promise.

Animal Testing 98

Animal Testing Clinical Trials Pharmaceutical Companies FDA 98

Metabolite Tales Blog

MARCH 1, 2023

2017, 30, 1, 13–37 [link] 2a Drug Metab. 2010, 75, 9, 3141–3143 [link] 22 Clin Pharmacokinet. There is much to be learnt from the pathways described above but in general, the more nitrogens present in your ring, the less likely you are to see Phase I type oxidations of the ring itself. References 1 Chem. Food Drug Anal.

Metabolic Stability 52

Metabolic Stability Pharmacokinetics Drugs Science 52