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Professor Alan Trounson AO CEO, Executive Director, Cartherics Alan is the past President of the Californian Institute for Regenerative Medicine (2007-2014), the Californian state’s $3 billion stem cell agency driving research in stem cellbiology and facilitating the translation of stem cell discoveries into clinical therapies.
The chips can be modelled with primary cells, IPS derived stem cells or patient derived cells and potentiates to unlock molecular mechanisms that drive the disease pathophysiology, holding a greater promise. From 3D cell culture to organs-on-chips. Trends in CellBiology. 2010;328(5986):1662-8. Ingber DE.
Few journal articles were written about the project using her (or anyone’s) name before 2010. When Louis Miller, now Chief of Malaria CellBiology at the NIH, attended a malaria conference in Shanghai in 2008, he asked: Who discovered artemisinin? Nobody had an answer.
As such, it has been proposed that inhibiting CDK7 would provide a potent means of inhibiting cell cycle progression, which may be especially relevant given that there is compelling evidence from gene knockout studies in mice for lack of an absolute requirement for CDK2, CDK4 and CDK6 for the cell cycle at least in most cell types (M alumbres et al.,
Nature Reviews Genetics (2010). Link Is the cell really a machine? , Journal of Theoretical Biology (2019). Link The second wave of synthetic biology: from modules to systems , by Purnick P.E.M. & Nature Reviews Molecular CellBiology (2009). Nature Reviews Molecular CellBiology (2014).
Nature Reviews Genetics (2010). Link Is the cell really a machine? , Journal of Theoretical Biology (2019). Link The second wave of synthetic biology: from modules to systems , by Purnick P.E.M. & Nature Reviews Molecular CellBiology (2009). Nature Reviews Molecular CellBiology (2014).
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