Codon

JULY 27, 2023

CNGA3-achromatopsia is a hereditary disease that causes people to see in shades of gray. They’re talking about a patient who has a rare genetic disease. ” Gene-edited poplar tree stems appear red. The lighter stems are from wildtype poplar trees. From Sulis D.B. in Science. From McKyton et al. in Current Biology.

Therapies 52

Therapies RNA DNA Engineering 52

The Pharma Data

AUGUST 3, 2021

end-stage renal disease (ESRD) bundled payment system, dialysis clinics rapidly implemented new treatment protocols, switching patients from Parsabiv to generic oral cinacalcet. A Phase 2 study continues to enroll patients with chronic obstructive pulmonary disease. With Parsabiv’s inclusion in the U.S. AMG 714 / PRV-015.

Biosimilars 52

Biosimilars Production Treatment FDA 52

Codon

MARCH 24, 2024

In the case of semaglutide, those cells are Saccharomyces cerevisiae— also known as Baker’s yeast — engineered to secrete a peptide precursor that is later purified, chemically modified, packaged into an injectable or tablet form, and then shipped around the world. Continuing this method may not scale.

Engineering 86

Engineering Vaccine Production RNA 86

The Pharma Data

JUNE 18, 2021

The study met its primary endpoint of superior progression-free survival (PFS) as assessed by an independent review committee (IRC) with a HR 0.216 (95% CI, 0.131-0.357; p < 0.0001), demonstrating a reduction in the risk of disease progression or death for I+V of approximately 78% compared to C+O. . About the GLOW Study.

Treatment 52

Treatment Therapies FDA FDA Approval 52

The Pharma Data

JUNE 18, 2021

Undetectable minimal residual disease (uMRD) was achieved in 77% of patients in peripheral blood and 60% of patients in bone marrow. 2,3 CLL is predominately a disease of the elderly, with a median age at diagnosis of 70 years and is more common among men than women.

Treatment 40

Treatment FDA Therapies FDA Approval 40

Agency IQ

JUNE 16, 2023

See Asbestos Disease Awareness Organization v. This package would propose updates to the alternative work practice as appropriate based on the review and address the issues raised for reconsideration. Reported information would be used by EPA and other Federal agencies in considering the regulation of asbestos. 19-CV-03807.

Regulations 40

Regulations Compliance Production Science 40

Codon

MAY 30, 2023

This means that IscB base editors might be easier to package inside of AAVs, which can only store 4,700 bases of DNA for gene therapies. Malaria deaths plummeted between 2010 and 2015, thanks mostly to the billions of dollars in philanthropic funding that were used to purchase bed nets and medicines. This paper is a big deal!

DNA 52

DNA RNA Engineering Vaccine 52

Codon

MAY 30, 2023

This means that IscB base editors might be easier to package inside of AAVs, which can only store 4,700 bases of DNA for gene therapies. Malaria deaths plummeted between 2010 and 2015, thanks mostly to the billions of dollars in philanthropic funding that were used to purchase bed nets and medicines. This paper is a big deal!

DNA 52

DNA RNA Engineering Vaccine 52

Codon

JANUARY 21, 2024

Today, refined versions of these human challenge studies have become standard practice in testing vaccines for vector-borne diseases (e.g., yellow fever, malaria, and dengue), evaluating new drugs or treatments, and studying pathogenesis, the process by which a disease develops. How are disease targets selected for challenge trials?

Vaccine 128

Vaccine Trials Disease Treatment 128

Agency IQ

JULY 12, 2024

Specifically, FDA is proposing to classify blood irradiators intended for the prevention of transfusion-associated graft versus host disease into Class II and blood irradiators intended for prevention of metastasis by irradiating intra-operatively salvaged blood of cancer patients undergoing surgery into Class III.

Regulations 40

Regulations FDA Science Production 40

Codon

FEBRUARY 9, 2025

” Indeed, Gage’s case initiated a standard practice in neuroscience in which diseased or damaged brains are used to examine the connection between behavior and neuroanatomy — a method referred to as “ lesion studies.” Amazingly, Gage not only survived but is remembered as “the man who began neuroscience.”

Research 108

Research Disease Engineering Regulations 108

Codon

FEBRUARY 23, 2025

Countries supported by PEPFAR saw HIV cases drop by 52 percent in 2023 compared to 2010, outpacing the 39 percent global decline. For that reason, long-term preventatives are probably a better strategy for controlling the disease. Jerome Horwitz and Wolfram Ostertag. This has happened before with other drugs.

Clinical Trials 74

Clinical Trials Virus Vaccine DNA 74